Nephro-Pathology Quiz

Le résumé fourni par la source

Clinical scenario:A 52-year-old man with a 15-year history of poorly controlled hypertension presents to the emergency department with a sudden onset of severe headache, blurring of vision, and shortness of breath.On examination, his blood pressure is 240/135 mmHg, and he appears acutely ill.Fundus examination reveals bilateral papilledema with flame-shaped hemorrhages and cotton-wool spots, consistent with hypertensive retinopathy grade IV.Laboratory investigations show serum creatinine of 3.5 mg/dL (baseline 1.2 mg/dL six months prior), elevated urea, and microscopic hematuria with mild proteinuria.Hematology demonstrates microangiopathic hemolytic anemia with schistocytes and thrombocytopenia.Urinalysis reveals red blood cell casts.A renal biopsy is performed.Representative images of the renal biopsy stained by a number of stains are provided below:

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