Development and validation of a prediction model based on a nomogram for tuberculous pleural effusion
Rattachement africain : cn. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Diagnosing tuberculous pleural effusion (TPE) is challenging. There is a lack of cross-sectional lateral comparisons among TPE prediction models. Objectives: We aimed to develop and validate a novel TPE prediction model and compare its diagnostic performance with that of existing models. Methods: Patients with pleural effusion were included in the training, testing, and external validation sets. Variable selection strategies included LASSO and logistic regression. The discriminability, calibration, and clinical efficacy of the prediction model were estimated in the three sets. The performance of the model was compared with that of two existing prediction models. Results: Fever, tuberculosis interferon-gamma release assays, pleural adenosine deaminase, the pleural mononuclear cell ratio, the ratio of pleural lactate dehydrogenase to pleural adenosine deaminase, pleural carcinoembryonic antigen, and pleural cytokeratin 19 fragment were selected to establish the prediction model. The AUCs were 0.931 (0.903-0.958), 0.856 (0.753-0.959), and 0.925 (0.867-0.984) in the training, testing, and external validation sets, respectively. The AUCs of the two existing prediction models were 0.793 (0.737-0.850) and 0.854 (0.816-0.892). The calibration curves revealed that this model had good consistency. Decision curve analysis revealed the acceptable clinical benefit of this model. Conclusion: Compared with the existing models, the TPE prediction model developed in this study demonstrated good diagnostic performance.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Development and validation of a prediction model based on a nomogram for tuberculous pleural effusion
- Date Crossref
- 18/07/2025
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Sichuan University State Key Laboratory of Biotherapy of China pays non établi dans la noticeUniversité ou école supérieure
-
West China Hospital of Sichuan University pays non établi dans la noticeÉtablissement de santé
-
The Sixth People's Hospital of Shenyang pays non établi dans la noticeÉtablissement de santé
-
Chengdu University of Traditional Chinese Medicine pays non établi dans la noticeUniversité ou école supérieure
-
Tibet Autonomous Region People's Hospital pays non établi dans la noticeÉtablissement de santé
-
Sixth People's Hospital of Chengdu Department of Respiratory and Critical Care Medicine pays non établi dans la noticeÉtablissement de santé
-
Key Laboratory of Acupuncture for Senile Disease (Chengdu University of TCM) pays non établi dans la noticeUniversité ou école supérieure
-
The Third People's Hospital of Tibet Autonomous Region Department of Tuberculosis pays non établi dans la noticeStructure de recherche
State Key Laboratory of Biotherapy of China — Sichuan University, West China Hospital of Sichuan University et The Sixth People's Hospital of Shenyang, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.