Serum Calcium Levels, Erythrocyte Indices, and Associated Factors in Children with Febrile Seizures
Rattachement africain : tr. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Febrile seizures (FS) are the most common seizures in childhood. In most studies, iron deficiency was associated with FS, whereas serum calcium (Ca) levels were contradictory. This study evaluated the relationships of erythrocyte indices, serum Ca levels, and related factors among children with FS. Prospectively, patients aged six months to five years were included in the complex FS (n = 23), simple FS (n = 22) and febrile without seizure groups (n = 25). Patients with central nervous system infection, previous afebrile seizures, or chronic drug use were excluded. Total and ionized Ca, inorganic phosphate, vitamin D levels, erythrocyte count and indices, hemoglobin, hematocrit, pH, bicarbonate and lactate levels in blood were examined. The cutoff values of variables discriminating between the FS and control groups were established through receiver operating characteristic analysis. In the complex FS group, Ca and mean corpuscular hemoglobin concentration (MCHC) levels were lower than those in the control group (p = 0.004 for both) and albumin levels were lower than those in the simple FS group (p = 0.02). Ca levels were positively correlated with MCHC (r = 0.252, p = 0.039). In the FS group, the proportions of MCHC < 34.1 g/dL, Ca < 9.9 mg/dL, ionized Ca < 1.27 mmol/L and pH < 7.38 were more frequent (p = 0.003, p = 0.005, p = 0.044 and p = 0.035 respectively). Lower Ca and MCHC levels were associated with FS. The positive correlation between Ca and MCHC levels indicates a common pathogenetic mechanism. To our knowledge, the increased proportion of patients with low blood pH level in FS is a novel finding.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Serum Calcium Levels, Erythrocyte Indices, and Associated Factors in Children with Febrile Seizures
- Date Crossref
- 30/06/2025
- Éditeur
- Tıp Fakültesi, Karadeniz Teknik Üniversitesi
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Karadeniz Technical University pays non établi dans la noticeUniversité ou école supérieure
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Zonguldak Bülent Ecevit University pays non établi dans la noticeUniversité ou école supérieure
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Sağlık Bilimleri Üniversitesi pays non établi dans la noticeUniversité ou école supérieure
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Karadeniz Teknik Üniversitesi Tıp Fakültesi pays non établi dans la noticeUniversité ou école supérieure
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Bülent Ecevit Üniversitesi pays non établi dans la noticeUniversité ou école supérieure
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İmperial Hastanesi pays non établi dans la noticeInstitution
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SAĞLIK BİLİMLERİ ÜNİVERSİTESİ pays non établi dans la noticeUniversité ou école supérieure
Karadeniz Technical University, Zonguldak Bülent Ecevit University et Sağlık Bilimleri Üniversitesi, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.