Coronary-type stent implantation in chronic thromboembolic pulmonary hypertension: a national registry case series
Rattachement africain : rs, it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Balloon pulmonary angioplasty (BPA) and pulmonary endarterectomy (PEA) are established treatments for chronic thromboembolic pulmonary hypertension (CTEPH). In cases where BPA is ineffective, stent implantation emerges as salvage therapy. However, stent implantation during BPA remains a subject of debate. METHODS: This seven-year case series in Serbia, where PEA is unavailable, examines outcomes in 10 CTEPH patients undergoing BPA with coronary-type stent implantation during BPA. Objectives include assessing the feasibility, safety, and efficacy of this combined approach, identifying optimal patient selection criteria. Criteria for stent placement included persistent unsatisfactory flow post-multiple balloon dilatations. Follow-up assessments were via repeat pulmonary angiography. RESULTS: Stents were successfully deployed, demonstrating sustained patency in 14 of 15 stents over an average 21.5-month (ranging from 11 up to 82 months) follow-up. Outcomes revealed significant reductions in mean pulmonary artery pressure, improvements in WHO Functional Class, and enhanced 6-minute walking distance. For the first 6 months, patients received daily clopidogrel 75 mg and rivaroxaban 15 mg, without significant bleeding. Dual therapy for pulmonary hypertension was consistently upheld. During the follow-up period, no stent thrombosis, restenosis, or other severe acute or chronic complications were observed; however, in one case, additional balloon stent post-dilatation was required. CONCLUSION: Coronary-type stent implantation during BPA for selected CTEPH patients, though not a primary treatment, proved valuable, offering a potential solution when BPA alone falls short. This case series emphasizes the need to refine patient selection criteria for this emerging therapeutic avenue.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Coronary-type stent implantation in chronic thromboembolic pulmonary hypertension: a national registry case series
- Date Crossref
- 30/06/2025
- Éditeur
- VM Media Group sp. z o.o
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Military Medical Academy pays non établi dans la noticeÉtablissement de santé
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University of Novi Sad pays non établi dans la noticeUniversité ou école supérieure
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Institute for Pulmonary Diseases of Vojvodina pays non établi dans la noticeÉtablissement de santé
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Scientific Veterinary Institute "Novi Sad" pays non établi dans la noticeStructure de recherche
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European Hospital pays non établi dans la noticeÉtablissement de santé
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Clinic of Cardiology pays non établi dans la noticeÉtablissement de santé
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European Health Centre Department of Pulmonary Circulation pays non établi dans la noticeÉtablissement de santé
Military Medical Academy, University of Novi Sad et Institute for Pulmonary Diseases of Vojvodina, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.