Atrial fibrillation in patients with heart failure with reduced, mildly reduced, and preserved ejection fraction: A report from the HEart failuRe ObsErvational Study (HEROES)
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Le résumé fourni par la source
BACKGROUND: Heart failure (HF) and atrial fibrillation (AF) often coexist and modify each other's course. The prevalence and clinical characteristics of AF differ in specific HF subtypes. AIMS: The study aimed to evaluate the incidence and clinical features of people with AF in comparison to those with sinus rhythm in HF, across the three HF subtypes categorized by left ventricular ejection fraction (EF). MATERIAL AND METHODS: Hospitalized patients and outpatients were enrolled in the Heart failuRe ObsErvational Study - a prospective, multicenter cohort study. HF subtypes were defined as reduced EF (HFrEF, EF <40%), mildly reduced EF (HFmrEF, EF 40%-49%), or preserved EF (HFpEF, EF ≥50%). RESULTS: A total of 1210 patients with HF were included in the study (71.8% male). Among them, 51.8% had HFrEF, 21.7% had HFmrEF, and 26.5% had HFpEF. Within the entire HF study population, 79.5% were hospitalized, and AF was present in 51.8% of patients. The prevalence of AF was 53.9% in HFrEF, 49.7% in HFmrEF, and 51.7% in HFpEF (P = 0.59). The strongest factors independently associated with AF in different HF subtypes were echocardiographic abnormalities: aortic regurgitation in patients with HFpEF (OR, 9.02; CI, 1.14-71.27; P <0.001), left atrial volume > median in patients with HFmrEF (OR, 6.21; CI, 2.24-17.2; P <0.001) and in patients with HFrEF (OR, 3.9; CI, 2.21-6.90; P <0.001). Selected independent associations with AF were similar in the HFpEF, HFmrEF, and HFrEF groups. CONCLUSIONS: In the population with HF, the AF incidence is similar in the HFrEF, HFmrEF, and HFpEF groups. It is associated with similar clinical characteristics in HF subtypes.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Atrial fibrillation in patients with heart failure with reduced, mildly reduced, and preserved ejection fraction: A report from the HEart failuRe ObsErvational Study (HEROES)
- Date Crossref
- 30/06/2025
- Éditeur
- Polskie Towarzystwo Kardiologiczne
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Jan Kochanowski University Collegium Medicum pays non établi dans la noticeUniversité ou école supérieure
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Wojskowy Instytut Medycyny Lotniczej pays non établi dans la noticeStructure de recherche
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Medical University of Warsaw Department of Cardiology pays non établi dans la noticeUniversité ou école supérieure
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Ministry of Interior and Administration pays non établi dans la noticeOrganisme public
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Central Clinical Hospital pays non établi dans la noticeÉtablissement de santé
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Jagiellonian University Department of Coronary Disease and Heart Failure pays non établi dans la noticeUniversité ou école supérieure
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Institute of Cardiology pays non établi dans la noticeStructure de recherche
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Corona (Poland) pays non établi dans la noticeEntreprise
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Wroclaw Medical University Institute of Heart Diseases pays non établi dans la noticeUniversité ou école supérieure
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Gdańsk Medical University pays non établi dans la noticeUniversité ou école supérieure
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Medical University of Lodz Department of Internal Diseases and Clinical Pharmacology pays non établi dans la noticeUniversité ou école supérieure
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Military Institute of Medicine Department of Cardiology and Internal Diseases pays non établi dans la noticeStructure de recherche
Collegium Medicum — Jan Kochanowski University, Wojskowy Instytut Medycyny Lotniczej et Department of Cardiology — Medical University of Warsaw, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.