Accès ouvert
2026
article
OpenAlex
Michał Tkaczyszyn, Mateusz Guzik, Gracjan Iwanek, Robert Zymliński et autres
INTRODUCTION: We hypothesized that de novo acute heart failure (AHF) and worsening of pre-existing HF (WHF) reflect distinct underlying metabolic states. OBJECTIVES: Our aim was to compare the circulating metabolomic and lipidomic profiles in de novo AHF and WHF. PATIENTS AND METHODS: …
pl
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2026
article
OpenAlex
Krzysztof Michał Górniak, W H Lis, Michał Tkaczyszyn, Krzysztof Aleksandrowicz et autres
Abstract Introduction Fabry disease is a systemic disorder that not only leads to left ventricular hypertrophy but also affects many other organs. One of these manifestations may be malnutrition, which would represent a potential therapeutic target. Purpose The aim of this study …
pl
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Accès ouvert
2026
article
OpenAlex
Michał Tkaczyszyn, Agnieszka Kapłon-Cieślicka, Maciej Janiszewski, Dominika Klimczak‐Tomaniak et autres
Heart failure (HF) management has evolved substantially over recent decades, transitioning from predominantly symptomatic treatment to a strategy grounded in disease-modifying therapies that improve survival and reduce hospitalizations. This review provides a structured and clinically oriented synthesis of landmark randomized controlled trials …
pl, de, ro, fr, es, ca, it
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Accès ouvert
2026
article
OpenAlex
Adrian Bednarek, Zuzanna Wojdyńska, Katarzyna Byczkowska, I Kowalik et autres
BACKGROUND: In heart failure (HF), patients' quality of life (QoL) is influenced not only by cardiacfunction but also by coexisting conditions. Despite the widespread use of QoL assessments, therole of patient-related factors as determinants of QoL remains not fully elucidated. AIMS: This …
pl
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Accès ouvert
2026
article
OpenAlex
Maciej T. Wybraniec, Artur Sufryd, Małgorzata Cichoń, Tomasz Tokarek et autres
AIMS: Cardiogenic shock (CS) represents an ominous complication of acute myocardial infarction (AMI) with a mortality rate exceeding 50%. The aim of the study was to evaluate current management, outcomes, and risk factors of mortality of AMI-related CS. METHODS: This snapshot registry …
pl, nl, gb
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Accès ouvert
2026
article
OpenAlex
Michał Tkaczyszyn
The growing awareness of cardiologists regarding amyloid transthyretin cardiomyopathy (ATTR-CM), together with increasingly precise non-invasive diagnostic approaches—particularly the development of practical diagnostic algorithms that streamline and facilitate the interpretation of parallel nuclear medicine and haematology tests—and finally, the dynamic progress of targeted …
pl
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Accès ouvert
2026
article
OpenAlex
Jan Biegus, Antoni Bayés‐Genís, Stephan von Haehling, Wojciech Kosmala et autres
Heart failure (HF) remains a major global health challenge, characterized by high morbidity, mortality, and healthcare costs despite substantial advances in pharmacological, device-based, and structural therapies. Its increasing prevalence reflects population ageing, improved survival after myocardial infarction, and the rising burden of …
pl, es, de, hu, se
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Accès ouvert
2025
article
OpenAlex
Carsten Tschöpe, Michał Tkaczyszyn
For many years, transthyretin cardiac amyloidosis (ATTR-CM) lived in the blind spot of routine cardiology [1].Across Europe, patients with heart failure with preserved ejection fraction (HFpEF), unexplained left ventricular wall thickening, atrial arrhythmia, or low-flow aortic stenosis were often managed symptomatically long …
de, pl
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2025
article
OpenAlex
Paweł Krzesiński, A A Galas, Robert Morawiec, M Grabowski et autres
Abstract Introduction Guideline-directed medical therapy (GDMT) is recommended in patients with heart failure and reduced ejection fraction (HFrEF) to reduce hospitalizations and mortality. Every medical contact, including hospitalization, should be used to initiate or up-titrate GDMT. However, still only a few patients …
us, pl
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2025
article
OpenAlex
Robert Morawiec, Paweł Maeser, Maciej Nadel, Agata Anna Galas et autres
Abstract Over recent years, heart failure (HF) with supranormal ejection fraction (snEF) has been postulated as a distinct phenotype of heart failure. It has been proven that patients with snEF (defined as EF ≥60% or ≥65%, depending on the analysis) have a …
pl, us
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2025
article
OpenAlex
Adrian Bednarek, Zuzanna Wojdyńska, Katarzyna Byczkowska, I Kowalik et autres
Abstract Background Novel therapies for heart failure (HF) are introduced not only to prevent clinical events but also to improve patients' quality of life (QoL). HF patients often present with multiple non-cardiac comorbidities, which may impact their prognosis and patient-reported outcomes. Despite …
pl, us
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2025
article
OpenAlex
Jaroslaw D Kasprzak, Robert Morawiec, Agata Anna Galas, Agata Tymińska et autres
Abstract Aim HEart failuRe ObsErvational Study of the Polish Cardiac Society (HEROES) is a prospective, multi-center, observational all-comers study aimed to assess clinical profile of heart failure (HF) pts (patients) in a representative national sample (41 centers). This analysis reports aspects of …
pl, us
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