Changes in enteric fever trends during the COVID-19 pandemic from the Surveillance for Enteric Fever in Asia Project: a cross-sectional study
Rattachement africain : bd, np, pk, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: . Paratyphi) to provide an evidence base for prevention and control measures in Bangladesh, Nepal, and Pakistan. Methods: From October 2020 to September 2022, we conducted prospective clinical surveillance and retrospective laboratory surveillance at health facilities in Dhaka, Bangladesh; Kathmandu and Kavrepalanchok, Nepal; and Karachi, Pakistan. Patients were eligible if they were outpatients with three or more days of fever in the last week. In Nepal and Pakistan, inpatients were eligible if they had suspected or confirmed enteric fever; in Bangladesh, only inpatients with confirmed enteric fever were enrolled. Patients with blood culture-confirmed enteric fever identified by hospital laboratories and laboratory network sites were also enrolled. Patients completed interviews and medical records were reviewed and abstracted. All enrolled patients had blood cultures performed. Antibiograms were performed to characterize drug sensitivity. We summarized the data descriptively. Findings: A total of 17,593 patients were enrolled from 19 facilities. Of these, 8410 patients had culture-confirmed enteric fever. Case counts in all countries decreased in the early stages of the COVID-19 pandemic, but increased over time in Bangladesh and Pakistan. Case counts remained low throughout the study period in Nepal. In all countries, typhoid was more common than paratyphoid; the proportion of paratyphoid cases ranged from 8.4% in Pakistan to 16% in Nepal. Extensively drug-resistant typhoid was common in Pakistan (69%), but was not detected in Bangladesh or Nepal. Interpretation: Cases of enteric fever decreased during the COVID-19 pandemic, though it is not clear how much of this decrease relates to true changes in transmission versus health-seeking behavior. Funding: This project was funded by the Gates Foundation through INV-008335.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Changes in enteric fever trends during the COVID-19 pandemic from the Surveillance for Enteric Fever in Asia Project: a cross-sectional study
- Date Crossref
- 01/04/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Child Health Research Foundation pays non établi dans la noticeOrganisation à but non lucratif
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Dhulikhel Hospital Center for Infectious Disease Research & Surveillance pays non établi dans la noticeÉtablissement de santé
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Kathmandu University pays non établi dans la noticeUniversité ou école supérieure
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Aga Khan University Department of Pediatrics and Child Health pays non établi dans la noticeUniversité ou école supérieure
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Sabin Vaccine Institute pays non établi dans la noticeOrganisation à but non lucratif
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Jinnah Postgraduate Medical Center pays non établi dans la noticeÉtablissement de santé
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Kharadar General Hospital pays non établi dans la noticeÉtablissement de santé
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National Institute of Child Health pays non établi dans la noticeÉtablissement de santé
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Stanford University Division of Infectious Diseases and Geographic Medicine pays non établi dans la noticeUniversité ou école supérieure
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Clinical Laboratory pays non établi dans la noticeStructure de recherche
Child Health Research Foundation, Center for Infectious Disease Research & Surveillance — Dhulikhel Hospital et Kathmandu University, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.