Recent Advances in Fluorescence Resonance Energy Transfer (FRET) Biosensors for Exosomes
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Le résumé fourni par la source
Cancer is a significant global health challenge, where early diagnosis is crucial for enhancing patient survival and mitigating the treatment burden on patients. Exosomes are extracellular vesicles released through the fusion of multivesicular bodies with cell membranes, carrying disease-associated information from donor cells. This makes exosomes a key biomarker in liquid biopsy analysis, particularly for early cancer detection. Developing cost-effective, straightforward, and sensitive exosome biosensing technologies is of significant practical importance. To date, a large number of fluorescence-based exosome biosensors have relied on the Fluorescence Resonance Energy Transfer (FRET) principle. This review introduces the basic background of the field and the principle of FRET-based exosome sensors, followed by a systematic summary of their progress categorized by different transduction elements or mechanisms. Finally, this work discusses the current challenges in the field and proposes potential solutions and future prospects, aiming to encourage and inspire the development of new approaches for advanced FRET exosome biosensors.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Recent Advances in Fluorescence Resonance Energy Transfer (FRET) Biosensors for Exosomes
- Date Crossref
- 28/03/2025
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Guangdong Medical College pays non établi dans la noticeUniversité ou école supérieure
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School of Pharmacy and Dongguan Innovation Institute Dongguan Key Laboratory of Advanced Drug Delivery and Biosensing Research and Development pays non établi dans la noticeUniversité ou école supérieure
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The 2nd Affiliated Hospital of Guangdong Medical University Key Laboratory of Liver Injury Diagnosis and Repair pays non établi dans la noticeUniversité ou école supérieure
Guangdong Medical College, Dongguan Key Laboratory of Advanced Drug Delivery and Biosensing Research and Development — School of Pharmacy and Dongguan Innovation Institute et Key Laboratory of Liver Injury Diagnosis and Repair — The 2nd Affiliated Hospital of Guangdong Medical University.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.