Day-to-Day Blood Pressure Variability and Cognitive Function in the Elderly With Acute Heart Failure
Rattachement africain : jp, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Heart failure (HF) and cognitive impairment often occur together in older adults. Although earlier studies have reported an association between blood pressure (BP) variability (BPV) and cognitive impairment, the underlying pathophysiology remains unclear in HF. In this study, the hypothesis that higher BPV is associated with cognitive impairment was evaluated in the elderly patients with acute decompensated HF (ADHF). METHODS: Day-to-day in-hospital BPV and cognitive function using a mini-mental state examination (MMSE) were assessed in 245 elderly patients (82.9 ± 6.0 years, 49.4% male) with ADHF. Based on the data of 7 days, day-to-day BPV (expressed as the standard deviation [SD], coefficient of variation [CV], maximum BP, minimum BP, and δ [maximum-minimum] BP) were measured. RESULTS: According to MMSE score quartiles, significant differences were observed in SD (8.2 vs. 6.2 vs. 6.7 mmHg, P < 0.001), CV (13.3 vs. 9.94 vs. 10.9 %, P < 0.001) and δ (22.8 vs. 17.5 vs. 18.6 mmHg, P < 0.001) in diastolic BP (DBP) between three groups. In the logistic regression analysis adjusted for the confounders, SD (OR: 1.23, P < 0.01), CV (OR: 1.12, P < 0.01), maximum (OR: 1.13, P < 0.001) and δ (OR: 1.07, P < 0.01) in DBP were significantly associated with the lowest quartile of MMSE score. In the stratified analysis by HF phenotypes, significant associations of day-to-day DBP variability were found with the lowest quartile of MMSE score specifically in the HF with preserved ejection fraction group (HFpEF). CONCLUSIONS: Cognitive impairment in association with day-to-day BPV is increasingly prevalent in elderly patients presenting with ADHF, specifically in HFpEF.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Day-to-Day Blood Pressure Variability and Cognitive Function in the Elderly With Acute Heart Failure
- Date Crossref
- 12/03/2025
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Hiroshima City Asa Citizens Hospital pays non établi dans la noticeÉtablissement de santé
-
University of Oklahoma Health Sciences Center pays non établi dans la noticeÉtablissement de santé
-
Hiroshima University pays non établi dans la noticeUniversité ou école supérieure
-
University of Oklahoma Health Science Center Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
-
Hiroshima City Asa Hospital Department of Cardiology pays non établi dans la noticeÉtablissement de santé
-
Graduate School of Biomedical and Health Sciences Department of Cardiovascular Medicine pays non établi dans la noticeUniversité ou école supérieure
Hiroshima City Asa Citizens Hospital, University of Oklahoma Health Sciences Center et Hiroshima University, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.