Recanalization for Symptomatic Non-acute Intracranial Large Vessel Occlusion: An Observational Study
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Le résumé fourni par la source
AIM: This study investigated the efficacy and safety of endovascular revascularization for symptomatic non-acute atherosclerotic intracranial LVO. METHODS: For non-acute atherosclerotic intracranial large vessel occlusion (LVO), despite aggressive medical treatment, recurrent ischemic stroke or transient ischemic attack related to the occluded artery still occurs repeatedly. This retrospective cohort study included stroke patients with intracranial LVO who received endovascular treatment (EVT), categorized by successful recanalization and the time interval from symptom onset to revascularization (＜30 days vs. ≥ 30 days). The primary efficacy outcome was stroke recurrence or mortality at the 6-month follow-up. RESULTS: Of the 264 patients in the study, 229 (87%) had successful recanalization, while 35 (13%) did not. In addition, 139 patients had recanalization times ≤ 30 days, and 125 had recanalization times ＞30 days. The successful recanalization group had a significantly lower rate of stroke recurrence or death during follow-up than the unsuccessful group (9.6% vs. 31.4%, adjusted odds ratio [OR]: 4.98, 95% confidence interval [CI]: 1.86 -13.37; P = 0.001). The group with a recanalization time ≤ 30 days also demonstrated a significantly lower rate of stroke recurrence or death during follow-up than the group with a recanalization time ＞30 days (7.9% vs.17.6%, P = 0.015). In addition, the rate of a favorable prognosis (modified Rankin Scale [mRS] 0-2) during the follow-up period was significantly higher in the successful recanalization group than in the successful recanalization group (71.1% vs. 51.4%, P = 0.021). CONCLUSION: These findings suggest that successful recanalization may have therapeutic potential for patients with non-acute intracranial large-vessel occlusion, particularly for those with LVO recanalization lasting ＜30 days, who show more significant benefits than those with longer-lasting recanalization [please check this carefully].
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Recanalization for Symptomatic Non-acute Intracranial Large Vessel Occlusion: An Observational Study
- Date Crossref
- 01/10/2025
- Éditeur
- Japan Atherosclerosis Society
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Shandong Provincial QianFoShan Hospital pays non établi dans la noticeÉtablissement de santé
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Shandong First Medical University Department of Neurology pays non établi dans la noticeUniversité ou école supérieure
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Qilu University of Technology Shandong Artificial Intelligence Institute pays non établi dans la noticeUniversité ou école supérieure
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Shandong Academy of Sciences pays non établi dans la noticeUniversité ou école supérieure
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Weifang People's Hospital pays non établi dans la noticeÉtablissement de santé
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Minzu University of China pays non établi dans la noticeUniversité ou école supérieure
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Weifang Hanting District People’s Hospital Department of Neurology pays non établi dans la noticeÉtablissement de santé
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Medical Faculty pays non établi dans la noticeUniversité ou école supérieure
Shandong Provincial QianFoShan Hospital, Department of Neurology — Shandong First Medical University et Shandong Artificial Intelligence Institute — Qilu University of Technology, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.