Analytic and Monte Carlo calculations of dose-mean lineal energy for 1 MeV–1 GeV protons with application to radiation protection quality factor
Rattachement africain : gr, jp, es, us, fr, de, nl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Radiation quality for determining biological effects is commonly linked to the microdosimetric quantity lineal energy ( $$y$$ y ) and to the dose-mean lineal energy ( $${y}_{\text{D}}$$ y D ). Calculations of $${y}_{\text{D}}$$ y D are typically performed by specialised Monte Carlo track-structure (MCTS) codes, which can be time-intensive. Thus, microdosimetry-based analytic models are potentially useful for practical calculations. Analytic model calculations of proton $${y}_{\text{D}}$$ y D and radiation protection quality factor ( $$Q$$ Q ) values in sub-micron liquid water spheres (diameter 10–1000 nm) over a broad energy range (1 MeV–1 GeV) are compared against MCTS simulations by PHITS, RITRACKS, and Geant4-DNA. Additionally, an improved analytic microdosimetry model is proposed. The original analytic model of Xapsos is refined and model parameters are updated based on Geant4-DNA physics model. Direct proton energy deposition is described by an alternative energy-loss straggling distribution and the contribution of secondary electrons is calculated using the dielectric formulation of the relativistic Born approximation. MCTS simulations of proton $${y}_{\text{D}}$$ y D values using the latest versions of the PHITS, RITRACKS, and Geant4-DNA are reported along with the Monte Carlo Damage Simulation (MCDS) algorithm. The $${y}_{\text{D}}$$ y D datasets are then used within the Theory of Dual Radiation Action (TDRA) to illustrate variations in $$Q$$ Q with proton energy. By a careful selection of parameters, overall differences at the ~ 10% level between the proposed analytic model and the MCTS codes can be attained, significantly improving upon existing models. MCDS estimates of $${y}_{\text{D}}$$ y D are generally much lower than estimates from MCTS simulations. The differences of $$Q$$ Q among the examined methods are somewhat smaller than those of $${y}_{\text{D}}$$ y D . Still, estimates of proton $$Q$$ Q values by the present model are in better agreement with MCTS-based estimates than the existing analytic models. An improved microdosimetry-based analytic model is presented for calculating proton $${y}_{\text{D}}$$ y D values over a broad range of proton energies (1 MeV–1 GeV) and target sizes (10–1000 nm) in very good agreement with state-of-the-art MCTS simulations. It is envisioned that the proposed model might be used as an alternative to CPU-intensive MCTS simulations and advance practical microdosimetry and quality factor calculations in medical, accelerator, and space radiation applications.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Analytic and Monte Carlo calculations of dose-mean lineal energy for 1 MeV–1 GeV protons with application to radiation protection quality factor
- Date Crossref
- 10/02/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Ioannina Medical Physics Laboratory pays non établi dans la noticeUniversité ou école supérieure
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Japan Atomic Energy Agency Research Group for Radiation Transport Analysis pays non établi dans la noticeOrganisme public
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Hokkaido University pays non établi dans la noticeUniversité ou école supérieure
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Universidad de Sevilla pays non établi dans la noticeUniversité ou école supérieure
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KBR (United States) pays non établi dans la noticeEntreprise
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University of Washington Department of Radiation Oncology pays non établi dans la noticeUniversité ou école supérieure
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Fred Hutch Cancer Center pays non établi dans la noticeOrganisation à but non lucratif
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Centre National de la Recherche Scientifique pays non établi dans la noticeOrganisme public
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Université de Bordeaux pays non établi dans la noticeUniversité ou école supérieure
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Laboratoire de Physique des deux infinis Bordeaux pays non établi dans la noticeStructure de recherche
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Federal Office for Radiation Protection pays non établi dans la noticeOrganisme public
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National and Kapodistrian University of Athens Department of Physics pays non établi dans la noticeUniversité ou école supérieure
Medical Physics Laboratory — University of Ioannina, Research Group for Radiation Transport Analysis — Japan Atomic Energy Agency et Hokkaido University, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.