Implications of a new clinical classification of acute myocardial infarction
Rattachement africain : ch, cl, gb, se, ru. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
AIMS: The diagnostic criteria for Type 2 myocardial infarction identify a heterogeneous group of patients with variable outcomes and no clear treatment implications. We aimed to determine the implications of a new clinical classification for myocardial infarction with more objective diagnostic criteria using cardiac imaging. METHODS AND RESULTS: In a prospective cohort study, patients with Type 2 myocardial infarction underwent coronary angiography and cardiac magnetic resonance imaging or echocardiography. The new classification was applied to identify (i) spontaneous myocardial infarction due to acute coronary pathology, (ii) secondary myocardial infarction precipitated by acute illness in the presence of obstructive coronary artery disease, a new regional wall motion abnormality, or infarct-pattern scarring, and (iii) no myocardial infarction in the absence of obstructive disease or new myocardial abnormality. In 100 patients (65 years, 43% women) with Type 2 myocardial infarction, the new classification identified 25 and 31 patients with spontaneous and secondary myocardial infarction, respectively, and 44 without myocardial infarction. Compared with patients without myocardial infarction, those with secondary myocardial infarction were older, had more risk factors, and had higher troponin concentrations (P < 0.05 for all). During a median follow-up of 4.4 years, death, myocardial infarction, or heart failure hospitalization was more common in secondary myocardial infarction compared with those without myocardial infarction [55% (17/31) vs. 16% (7/44), P < 0.001]. CONCLUSION: A new clinical classification of myocardial infarction informed by cardiac imaging would reduce the diagnosis of myocardial infarction in acute illness and identify those patients at highest risk who are most likely to benefit from treatment. CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/ct2/show/NCT03338504.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Implications of a new clinical classification of acute myocardial infarction
- Date Crossref
- 18/01/2025
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Basel pays non établi dans la noticeUniversité ou école supérieure
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University Hospital of Basel pays non établi dans la noticeÉtablissement de santé
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Hospital Base Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology pays non établi dans la noticeÉtablissement de santé
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University of Edinburgh Usher Institute pays non établi dans la noticeUniversité ou école supérieure
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Uppsala University Department of Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Department of Medical Sciences pays non établi dans la noticeOrganisme public
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BHF/University Centre for Cardiovascular Science pays non établi dans la noticeUniversité ou école supérieure
University of Basel, University Hospital of Basel et Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology — Hospital Base, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.