Efficacy of IV Paracetamol in Patients with Renal Colic in Emergency Department
Rattachement africain : pk. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Renal colic, characterized by excruciating flank pain radiating to the groin, arises from urinary tract obstruction, triggering prostaglandin production and increased intra-renal pressure. NSAIDs are the first-line analgesics but have limitations in vulnerable populations. Intravenous paracetamol has emerged as a safer alternative with rapid analgesic effects and fewer adverse outcomes, especially in resource-limited settings. Objective: The objective is to compare the analgesic efficacy of the intravenous paracetamol and intra muscular diclofenac sodium, in the early resolution of pain in acute renal colic. Methods: This randomized controlled trial was conducted from February 2024 to April 2024 at the Emergency Department of Mayo Hospital Lahore. Patients showing clinical signs and symptoms of acute renal colic were randomly assigned to two groups. Group I (n=35) received 1 gram of intravenous paracetamol, while Group II (n=35) was given 50 mg of intramuscular diclofenac sodium. The pain intensity was evaluated using the Verbal Rating Scale (VRS) 30 minutes after treatment. Results: In this study, there were 47 male patients and 23 female patients. The mean age was 38 12 years old. After 30 minutes of administration, the pain relief in the paracetamol group (p value: <0.01) was similar to that of diclofenac group (p value: <0.01). However, the requirement of rescue analgesia was lower in the paracetamol group than diclofenac group. Conclusion: In acute renal colic patients, with the heralded side effects of non-steroidal anti-inflammatory drugs, IV paracetamol is an excellent alternative, with low risk profile and a higher analgesic efficacy.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Efficacy of IV Paracetamol in Patients with Renal Colic in Emergency Department
- Date Crossref
- 31/12/2024
- Éditeur
- Indus Publishers
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Mayo Hospital Department of Emergency Medicine pays non établi dans la noticeÉtablissement de santé
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Services Institute of Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Services Hospital Department of Medicine pays non établi dans la noticeÉtablissement de santé
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Farooq Hospital pays non établi dans la noticeÉtablissement de santé
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CMH Lahore Medical College and Institute of Dentistry pays non établi dans la noticeÉtablissement de santé
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Shalamar Hospital Department of Urogynaecology pays non établi dans la noticeÉtablissement de santé
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Akhtar Saeed Teaching Hospital Intensive Care Unit (ICU) pays non établi dans la noticeÉtablissement de santé
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Rahbar Medical and Dental College Department of Anesthesia pays non établi dans la noticeUniversité ou école supérieure
Department of Emergency Medicine — Mayo Hospital, Services Institute of Medical Sciences et Department of Medicine — Services Hospital, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.