Immigrant Health and Early-Onset Colorectal Cancer Disparities: Results From the Spanish Early-Onset Colorectal Cancer Consortium
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Le résumé fourni par la source
PURPOSE To better understand immigration disparities among a Spanish Early-Onset Colorectal Cancer (SECOC) subset, according to the country of origin. PATIENTS AND METHODS We selected 250 consecutive participants from the SECOC consortium. Data on baseline patient and tumor characteristics, family history of colorectal cancer (CRC), and follow-up were collected. The presence of mismatch repair deficiency was also assessed. Special data regarding country of origin, time of stay in Spain in case of other different country, and a 10-year cutoff that specifies the obtaining of Spanish nationality defined the variables of interest for comparison. RESULTS Seventy-five percent of patients with early-onset CRC (EOCRC) (188) were born in Spain, whereas the other 25% were born outside of Spain. The mean time of living in Spain until the EOCRC diagnosis was 16.5 years. Comparatively, most of the analyzed features showed equivalent proportions between cohorts. Only Spanish patients appeared to have more familial cancer component in first degree in general (32.3%; P = .01), compared with non-Spaniards, which showed a predominant sporadic component (56.4%; P < .001). Among immigrants, those patients living in Spain before CRC diagnosis ≤10 years were younger at diagnosis (39.1 v 42.5), more frequently male (77.8 v 47.7), were in more advanced stages (88.8% diagnosed at stage III and IV [ P = .01]), and had a worse prognosis regarding recurrence rates (29.4% v 6.3%). CONCLUSION Although there were few differences between Spanish and non-Spanish EOCRC, the most remarkable difference was that linked with the situation of those immigrants who have recently arrived in Spain, in relation to their lower health coverage, which could be associated with the delay in the diagnosis and their subsequent worse prognosis.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Immigrant Health and Early-Onset Colorectal Cancer Disparities: Results From the Spanish Early-Onset Colorectal Cancer Consortium
- Date Crossref
- 01/11/2024
- Éditeur
- American Society of Clinical Oncology (ASCO)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Instituto de Investigación Biomédica de Salamanca pays non établi dans la noticeStructure de recherche
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Vall d'Hebron Hospital Universitari pays non établi dans la noticeÉtablissement de santé
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Universidad de Salamanca pays non établi dans la noticeUniversité ou école supérieure
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MD Anderson Cancer Center Madrid pays non établi dans la noticeÉtablissement de santé
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Hospital General Universitario Gregorio Marañón pays non établi dans la noticeÉtablissement de santé
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Hospital Universitario Infanta Leonor pays non établi dans la noticeÉtablissement de santé
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Hospital Clínico San Carlos pays non établi dans la noticeÉtablissement de santé
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Hospital Del Mar Surgery Department pays non établi dans la noticeÉtablissement de santé
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Hospital de Galdakao pays non établi dans la noticeÉtablissement de santé
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Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas pays non établi dans la noticeStructure de recherche
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Consorci Institut D'Investigacions Biomediques August Pi I Sunyer pays non établi dans la noticeStructure de recherche
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Universitat de Barcelona pays non établi dans la noticeUniversité ou école supérieure
Instituto de Investigación Biomédica de Salamanca, Vall d'Hebron Hospital Universitari et Universidad de Salamanca, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.