Ana Burdaspal

Multiple primary tumours in early-onset colorectal cancer: deciphering the risk

J Orgáz, Edgardo Celi Altamarina, Cristian Cisterne, Elena García García et autres

The prevalence of multiple primaries (MPs) in the same individual is reported to range from 2% to 17%1–4. Aetiological factors that may predispose individuals to MPs can be grouped into host-related (for example inherited cancer syndromes), lifestyle, and environmental factors5. Additionally, cancer …

Immigrant Health and Early-Onset Colorectal Cancer Disparities: Results From the Spanish Early-Onset Colorectal Cancer Consortium

José Perea, Marc Martí, Ariadna García-Rodríguez, Rosario Vidal Tocino et autres

PURPOSE To better understand immigration disparities among a Spanish Early-Onset Colorectal Cancer (SECOC) subset, according to the country of origin. PATIENTS AND METHODS We selected 250 consecutive participants from the SECOC consortium. Data on baseline patient and tumor characteristics, family history of …

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Chromosomal breaks: another differential gap between early-onset and late-onset colorectal cancers

José Perea, Juan Luis Garcı́a, Luis Antonio Corchete, Marc Martí et autres

Colorectal cancer remains the second most common cause of cancer-related death in Western countries in terms of incidence and mortality, and is the most common tumour type in both sexes1. Up to 10% of all patients with colorectal cancer are younger than …

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Familial component of early-onset colorectal cancer: opportunity for prevention

María Daca-Álvarez, Marc Martí, Antonino Spinelli, Noel F. F. C. de Miranda et autres

BACKGROUND: Individuals with a non-syndromic family history of colorectal cancer are known to have an increased risk. There is an opportunity to prevent early-onset colorectal cancer (age less than 50 years) (EOCRC) in this population. The aim was to explore the proportion …

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