Transforming diagnostic capacity by syndromic infection testing for remote isolated communities
Rattachement africain : gb, gi, ms, au, fk, in, ca, us, ky. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Objective Many of the UK overseas territories are small with limited microbiological diagnostic capacity for pathogens and antimicrobial resistance detection. The Covid-19 pandemic highlighted the particular vulnerability of these territories for the emergence of novel infections and antimicrobial resistance. Methods The UKHSA program with its territory partners implemented rapid automated syndromic molecular diagnostics (RASM), aiming to improve diagnostic capacity. Local laboratory staff were trained in the use of the diagnostics, and guidance was provided to clinicians for requesting tests. Syndromic diagnoses included enteric, respiratory, bloodstream, neurological infection, and antibiotic resistance mechanisms. Data on diagnostic capacity, turnaround times and clinical impact were collected from records before and after implementation of RASM. Results Turnaround time for results went from an average 14 days to 1 day, and often much shorter. Previously undiagnosed conditions, could now be identified to the microbiological level rapidly in territory, allowing appropriate specific clinical management, infection prevention, improved antimicrobial stewardship and rapid public health response. This technology is simple to operate and maintain with little scope for user error. The speed of microbiological diagnosis for patient management and public health detection and response was greatly enhanced. Conclusion Rapid microbiological diagnosis on site transformed patient management, the timely investigation and management of outbreaks and clusters, accurate surveillance and antimicrobial stewardship. Targeted RASM is cost effective, reducing the requirement for highly trained scientific staff and expensive logistics around rapid transport to reference laboratories. This innovation improves clinical care and strengthens local preparedness in communicable disease and public health response.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Transforming diagnostic capacity by syndromic infection testing for remote isolated communities
- Date Crossref
- 18/11/2024
- Éditeur
- openRxiv
- Type
- posted-content
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
UK Health Security Agency UK Overseas Territories Programme pays non établi dans la noticeOrganisme public
-
Gibraltar Health Authority pays non établi dans la noticeOrganisme public
-
Montserrat Volcano Observatory pays non établi dans la noticeStructure de recherche
-
King Edward Memorial Hospital pays non établi dans la noticeÉtablissement de santé
-
South Atlantic Environmental Research Institute pays non établi dans la noticeStructure de recherche
-
King Edward Memorial Hospital Research Centre pays non établi dans la noticeÉtablissement de santé
-
Island Health pays non établi dans la noticeÉtablissement de santé
-
St. Helena Hospital pays non établi dans la noticeÉtablissement de santé
-
Public Health Department pays non établi dans la noticeOrganisme public
-
University College of the Cayman Islands pays non établi dans la noticeUniversité ou école supérieure
-
Truman Bodden Law School pays non établi dans la noticeUniversité ou école supérieure
-
Ascension pays non établi dans la noticeÉtablissement de santé
UK Overseas Territories Programme — UK Health Security Agency, Gibraltar Health Authority et Montserrat Volcano Observatory, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.