High SARS-CoV-2 secondary infection rates in households with children in Georgia, United States, Fall 2020—Winter 2021
Rattachement africain : us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background A wide range of household secondary infection rates has been reported, and the role of children in population transmission dynamics for SARS-CoV-2 remains ill-defined. We sought to better understand household infection early in the pandemic. Methodology A cross-sectional study of 17 households in the Atlanta metropolitan area with at least one child and one case of COVID-19 in the prior 1–4 months were recruited between December 2020 and April 2021. Self-collected saliva samples were tested on a multiplexed platform to detect IgG antibodies that bind to SARS-CoV-2 antigens. Secondary infection rates (SIR) were calculated and compared. Results We report results on 17 families, including 66 individuals. We found an average SIR of 0.58; children and adults were similarly infected (62% children vs. 75% adults) (p = 0.2). Two out of 17 households had a pediatric index per our definition. Number of pediatric infections per household (p = 0.18), isolation (p = 0.34), and mask wearing (p = 0.80) did not differ significantly among households with an SIR above the mean vs. those with SIR below the mean. Households with higher SIR also had a higher number of symptomatic cases (p < 0.001). Discussion We demonstrated high household SIRs at the early stages of the pandemic in late 2020 to early 2021 with similar impact on children and adults. The ease of collecting saliva and the detection of asymptomatic infections highlight the advantages of this strategy and potential for scale-up.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- High SARS-CoV-2 secondary infection rates in households with children in Georgia, United States, Fall 2020—Winter 2021
- Date Crossref
- 25/10/2024
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Emory University Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Kaiser Permanente pays non établi dans la noticeOrganisation à but non lucratif
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Johns Hopkins University pays non établi dans la noticeUniversité ou école supérieure
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Children's Healthcare of Atlanta pays non établi dans la noticeÉtablissement de santé
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Rollins School of Public Health Hubert Department of Global Health pays non établi dans la noticeUniversité ou école supérieure
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The Southeast Permanente Medical Group pays non établi dans la noticeInstitution
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Johns Hopkins Bloomberg School of Public Health Department of Environmental Health and Engineering pays non établi dans la noticeUniversité ou école supérieure
Department of Medicine — Emory University, Kaiser Permanente et Johns Hopkins University, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.