Impact of mental disorders on low adherence to antiretroviral therapy in people living with HIV in Spain
Rattachement africain : es. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
The relationship between mental disorders other than depression or anxiety, and low adherence to both antiretroviral treatment (ART) and linkage to HIV care are unclear. The aim of our study was to compare the prevalence of mental disorders in people living with HIV (PLHIV) in Spain who present low versus high adherence to ART. We performed a cross-sectional study comparing two groups of PLHIV: 20 PLHIV with low adherence and 80 PLHIV with high adherence to ART. PLHIV who met at least one of the following criteria were included in the low-adherence group: virological failure (HIV-VL > 50 copies/mL in two consecutive blood samples); low attendance to scheduled clinical visits (≥2 missed visits in last year); irregular administration of ART (≥10 forgotten doses in the last month); and interruption of ART for more than 1 week. Inclusion criteria for high adherence were: PLHIV who had been on stable ART for more than 1 year with an HIV-VL below 50 copies/mL and without missed visits over the previous 12 months. The Millon Clinical Multiaxial Inventory was administered to participants. PLHIV with low adherence showed higher scores for all mental disorders compared with those with high adherence. And, in the multivariate binary logistic regression analysis, drug dependence and post-traumatic stress disorder were independently associated with low adherence (Nagelkerke R2 = 0.0686). In conclusion, PLHIV with poorly controlled HIV infection presented important psychological vulnerabilities. Mental health should be checked at the beginning of ART and during follow-up, especially in PLHIV with low adherence or low linkage to the health care system.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Impact of mental disorders on low adherence to antiretroviral therapy in people living with HIV in Spain
- Date Crossref
- 29/09/2024
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Alicante Department of Health Psychology pays non établi dans la noticeUniversité ou école supérieure
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Instituto de Salud Carlos III pays non établi dans la noticeOrganisation à but non lucratif
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Spanish Clinical Research Network pays non établi dans la noticeStructure de recherche
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Hospital General Universitario de Alicante Doctor Balmis pays non établi dans la noticeÉtablissement de santé
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Instituto de investigación sanitaria y biomédica de Alicante pays non établi dans la noticeStructure de recherche
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Universitat de Miguel Hernández d'Elx pays non établi dans la noticeUniversité ou école supérieure
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Alicante Institute for Health and Biomedical Research (ISABIAL) pays non établi dans la noticeStructure de recherche
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Alicante University General Hospital Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Carlos III Health Institute Spanish AIDS Research Network pays non établi dans la noticeStructure de recherche
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Miguel Hernandez University Department of Clinical Medicine pays non établi dans la noticeUniversité ou école supérieure
Department of Health Psychology — University of Alicante, Instituto de Salud Carlos III et Spanish Clinical Research Network, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.