A New Self-Expandable Metallic Stent with Low Axial Force and a High Axial Force Zero-Border Shows a Very Low Perforation Rate in Malignant Colorectal Obstruction: A Japanese Multicenter Prospective Study
Rattachement africain : jp. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Recently, there has been a significant increase in the utilization of self-expandable metallic stents (SEMSs) for treating malignant colorectal obstructions through colorectal stenting. The mechanical properties of SEMSs are usually considered to affect clinical outcomes of patients with malignant colorectal obstructions. Methods: This single-arm, prospective, multicenter study of SEMS with a lower axial force and high axial force zero-border included 200 patients with malignant colorectal obstruction. Technical and clinical success, stent patency, and adverse events associated with SEMS placement were evaluated. Results: One patient was excluded, and 199 patients were evaluated. The treatment intent was bridge-to-surgery in 129 and palliation in 70 patients. Technical and clinical success rates were 99.5% and 97.0%, respectively. The percentage of the ColoRectal Obstruction Scoring System scores of 3 or higher improved significantly from 19.2% before placement to 93.9% after placement. Clinical success was not achieved in five patients due to insufficient stent expansion in four patients and stent occlusion in one patient. Only one patient underwent emergency surgery for perforation of the proximal colon, far from where the stent was placed; the rescue procedure was not performed, despite no improvement in proximal dilatation due to insufficient stent expansion. Among the palliation cohort, 15 patients received chemotherapy, including molecular-targeted agents such as bevacizumab. There were no fatal cases related to stent placement. Conclusions: For management of malignant colorectal obstruction, this newly developed SEMS with low axial force and a high axial force zero-border showed high technical and clinical success rates, and an extremely low perforation rate (0.5%).
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A New Self-Expandable Metallic Stent with Low Axial Force and a High Axial Force Zero-Border Shows a Very Low Perforation Rate in Malignant Colorectal Obstruction: A Japanese Multicenter Prospective Study
- Date Crossref
- 28/08/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Juntendo University pays non établi dans la noticeUniversité ou école supérieure
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Hiroshima Prefectural Hospital Department of Gastroenterological Surgery pays non établi dans la noticeÉtablissement de santé
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Aomori Prefectural Central Hospital Department of Gastroenterology pays non établi dans la noticeÉtablissement de santé
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Toho University Department of Surgery pays non établi dans la noticeUniversité ou école supérieure
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Toho University Ohashi Medical Center pays non établi dans la noticeÉtablissement de santé
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Hiroshima University Hospital Gastrointestinal Endoscopy and Medicine pays non établi dans la noticeÉtablissement de santé
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Kure Medical Center Department of Gastroenterology pays non établi dans la noticeÉtablissement de santé
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Toho University Omori Medical Center pays non établi dans la noticeÉtablissement de santé
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Aichi Medical University Department of Gastroenterology pays non établi dans la noticeUniversité ou école supérieure
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Tokyo Metropolitan Tama Medical Center Department of Surgery pays non établi dans la noticeÉtablissement de santé
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Fukushima Medical University Department of Coloproctology pays non établi dans la noticeUniversité ou école supérieure
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Tokyo Women's Medical University Department of Surgery pays non établi dans la noticeUniversité ou école supérieure
Juntendo University, Department of Gastroenterological Surgery — Hiroshima Prefectural Hospital et Department of Gastroenterology — Aomori Prefectural Central Hospital, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.