Subject-specific analysis reveals spatially heterogeneous white matter abnormalities in sports-related concussion

Résumé fourni par la source

Sport-related concussion (SRC) injury inclines to cause subject-specific brain region abnormalities. This study applied subject-specific analysis that accounts for inter-subject variation to investigate heterogeneity of white matter alterations in a sample from a large national multicenter study, the Concussion Assessment, Research and Education Consortium. Our results demonstrated that subject-specific white matter abnormalities in SRC can be uncovered by calculating the extreme Z-score maps based on a template generated from normally distributed diffusion tensor imaging metric values in non-contact sports controls. Our finding indicates that the SRC-induced white matter abnormalities show heterogeneous spatial distribution across participants.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.