Association of neuroanatomical changes with neuropsychological changes in Treated Adult HIV-Positive Patients

Le résumé fourni par la source

This study was designed to use the structural MRI data to characterize volumetric changes in gray matter and white matter, and to determine variations in cortical thickness, in a group of HIV-infected individuals to understand how their brain structural changes are associated with their neuropsychological state compared to a group of healthy individuals with similar social, behavioral backgrounds. Despite the demographic similarities and cART, we observed reduced gray and white matter volumes, as well as altered cortical thickness in HIV-infected participants compared with healthy controls. In addition, the neuroanatomic changes in HIV-infected patients showed statistically significant correlations with memory scores.

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