Phytochemical and antibacterial studies on seeds of Sesbania grandiflora Linn.: A novel report

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Sesbania grandiflora Linn belonging to family Fabaceae is a well-recognized medicinal plant in numerous countries like India, Srilanka and Southeast Asia. The present study examines the phytochemical constituents and antimicrobial activity of seed of Sesbania grandiflora. The quantitative examination of numerous phytochemicals was analyzed in different solvent systems including Petroleum ether, Ethyl acetate, Ethanol, Methanol and Water. Preliminary phytochemical analysis revealed the presence of nine compounds such as alkaloids, flavonoids, phenol, quinones, saponins, steroids, proteins, tannins and terpenoids. A comparative antimicrobial activity of dried seed extract was evaluated against four pathogenic strains names Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella pneumoniae. Among the extracts studied, petroleum ether and ethyl acetate show highest antimicrobial activity. The phytochemical analysis revealed the presence of alkaloids, flavonoids, saponins, phenols, tannins, terpenoids, quinones, steroids and proteins. Twenty compounds were observed in extract of petroleum ether and about thirty compounds were observed in extract of ethyl acetate by GC-MS. The result suggest that the seeds are a rich source of valuable primary and secondary metabolites exhibiting the antimicrobial activity and no further studies were reported yet.

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