Women and men with distressing low sexual desire exhibit sexually dimorphic brain processing
Rattachement africain : gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Distressing low sexual desire, termed Hypoactive Sexual Desire Disorder (HSDD), affects approximately 10% of women and 8% of men. In women, the 'top-down' theory of HSDD describes hyperactivity in higher-level cognitive brain regions, suppressing lower-level emotional/sexual brain areas. However, it is unknown how this neurofunctional disturbance compares to HSDD in men. To investigate this, we employed task-based functional MRI in 32 women and 32 men with HSDD to measure sexual-brain processing during sexual versus non-sexual videos, as well as psychometric questionnaires to assess sexual desire/arousal. We demonstrate that women had greater activation in higher-level and lower-level brain regions, compared to men. Indeed, women who had greater hypothalamic activation in response to sexual videos, reported higher psychometric scores in the evaluative (r = 0.55, P = 0.001), motivational (r = 0.56, P = 0.003), and physiological (r = 0.57, P = 0.0006) domains of sexual desire and arousal after watching the sexual videos in the scanner. By contrast, no similar correlations were observed in men. Taken together, this is the first direct comparison of the neural correlates of distressing low sexual desire between women and men. The data supports the 'top-down' theory of HSDD in women, whereas in men HSDD appears to be associated with different neurofunctional processes.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Women and men with distressing low sexual desire exhibit sexually dimorphic brain processing
- Date Crossref
- 14/05/2024
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Invicro (United Kingdom) pays non établi dans la noticeEntreprise
-
Imperial College London Section of Endocrinology and Investigative Medicine pays non établi dans la noticeUniversité ou école supérieure
-
Imperial College Healthcare NHS Trust Jane Wadsworth Sexual Function Clinic pays non établi dans la noticeÉtablissement de santé
-
Invicro London pays non établi dans la noticeInstitution
-
Statsconsultancy Ltd pays non établi dans la noticeEntreprise
Invicro (United Kingdom), Section of Endocrinology and Investigative Medicine — Imperial College London et Jane Wadsworth Sexual Function Clinic — Imperial College Healthcare NHS Trust, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.