Supplementary materials for the manuscript "Association of HLA-class II alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population"

Le résumé fourni par la source

Supplementary Table S1. Association analysis of each HLA-DRB1 allele with occurrence of relapse and time to relapse. Supplementary Table S2. Association analysis of each HLA-DQA1 allele with occurrence of relapse and time to relapse. Supplementary Table S3. Association analysis of each HLA-DQB1 allele with occurrence of relapse and time to relapse. Supplementary Table S4. Association analysis of each HLA-DPB1 allele with occurrence of relapse and time to relapse. Supplementary Table S5 Association analyses of HLA-DRβ1_13S encoding alleles with susceptibility and relapse-free survival. Supplementary Figure S1. Sanger sequencing chromatograms around the HLA-DQA1*03:02 tagSNP rs11545686. Representative Sanger sequencing chromatograms corresponding to each of the three genotypes are shown. The rs11545686C allele tags HLA-DQA1*03:02. HLA-DQA1 genotype of each subject determined by PCR-SSOP was DQA1*03:02/03*02 (relapse ID 36), DQA1*03:02/05:07 (relapse ID 156) and DQA1* 01:01/01:02 (relapse ID 164), as shown in Supplementary Data 1. Supplementary Data 1. Clinical information and HLA genotypes in each subject examined for susceptibility and relapse. Susceptibility Data 2. Association of each HLA -class II amino acid with relapse-free survival.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.