Accès ouvert déclaré 2024 review

Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

Jamie L. Felton, María J. Redondo, Richard A. Oram, Cate Speake, S. Alice Long, Suna Önengüt-Gümüşcü, Stephen S. Rich, Gabriela S. F. Monaco, Arianna Harris-Kawano, Dianna Perez, Zeb Saeed, Benjamin Hoag, Rashmi Jain, Carmella Evans‐Molina, Linda A. DiMeglio, Heba M. Ismail, Dana Dabelea, Randi K. Johnson, Marzhan Urazbayeva, John M. Wentworth, Kurt Griffin, Emily K. Sims, Deirdre K. Tobias, Jordi Merino, Abrar Ahmad, Catherine Aiken, Jamie L. Benham, Dhanasekaran Bodhini, Amy L. Clark, Kevin Colclough, Rosa Corcoy, Sara J. Cromer, Daisy Duan, Ellen C. Francis, Pieter Gillard, Véronique Gingras, Romy Gaillard, Eram Haider, Alice E. Hughes, Jennifer M. Iklé, Laura M. Jacobsen, Anna R. Kahkoska, Jarno L. T. Kettunen, Raymond J. Kreienkamp, Lee‐Ling Lim, Jonna M. E. Männistö, Robert Massey, Niamh‐Maire Mclennan, Rachel G. Miller, Mario Luca Morieri, Jasper Most, Rochelle N. Naylor, Bige Ozkan, Kashyap Patel, Scott J. Pilla, Katsiaryna Prystupa, Sridharan Raghavan, Mary R. Rooney, Martin Schön, Zhila Semnani‐Azad, Magdalena Sevilla-González, Pernille Svalastoga, Wubet Worku Takele, Claudia H.T. Tam, Anne Cathrine B. Thuesen, Mustafa Tosur, Amelia S. Wallace, Caroline C. Wang, Jessie J. Wong, Jennifer M. Yamamoto, Katherine Young, Chloé Amouyal, Mette K. Andersen, Maxine P. Bonham, Mingling Chen, Feifei Cheng, Tinashe Chikowore, Sian C. Chivers, Christoffer Clemmensen, Adem Y. Dawed, Aaron J. Deutsch, Laura T. Dickens, Monika Dudenhöffer‐Pfeifer, María Mercè Fernández-Balsells, Hugo Fitipaldi, Stephanie L. Fitzpatrick, Stephen E. Gitelman, Mark O. Goodarzi, Jessica A. Grieger, Marta Guasch‐Ferré, Nahal Habibi, Torben Hansen, Chuiguo Huang, Angus G. Jones, Robert W. Koivula, Aaron Leong, Gloria K. W. Leung, Ingrid Libman, Kai Liu, William L. Lowe, Robert W. Morton, Ayesha A. Motala, James S. Pankow, Maleesa Pathirana, Sofia Pazmiño, John R. Petrie, Camille E. Powe, Alejandra Quinteros, Debashree Ray, Mathias Ried‐Larsen, Vanessa Santhakumar, Sarah Kanbour, Sudipa Sarkar, Denise Scholtens, Elizabeth Selvin, Wayne Huey‐Herng Sheu, Maggie A. Stanislawski, Nele Steenackers, Andrea K. Steck, Norbert Stefan, Julie Støy, Rachael W. Taylor, Sok Cin Tye, Gebresilasea Gendisha Ukke, Bart Van der Schueren, Camille Vatier, Wesley Hannah, Sara L. White, Gechang Yu, Yingchai Zhang, Shao J. Zhou, Jacques Beltrand, Michel Polak, Ingvild Aukrust, Elisa De Franco, Sarah E. Flanagan, Kristin A. Maloney, Andrew McGovern, Janne Molnes, Mariam Nakabuye, Pål R. Njølstad, Hugo Pomares‐Millan, Michele Provenzano, Cécile Saint‐Martin, Cuilin Zhang, Yeyi Zhu, Sungyoung Auh, Russell J. de Souza, Andrea J. Fawcett, Chandra Gruber, Eskedar Getie Mekonnen, Emily Mixter, Diana Sherifali, Robert H. Eckel, John J. Nolan, Louis H. Philipson, Rebecca J. Brown, Liana K. Billings, Kristen E. Boyle, Tina Costacou, John Dennis, José C. Florez, Anna L. Gloyn, Maria F. Gomez, Peter A. Gottlieb, Siri Atma W. Greeley, Andrew T. Hattersley, Irl B. Hirsch, Marie‐France Hivert, Korey K. Hood, Jami L. Josefson, Soo Heon Kwak, Lori M. Laffel, Siew Lim, Ruth J. F. Loos, Ronald C.W., Chantal Mathieu, Nestoras Mathioudakis, James B. Meigs, Shivani Misra, Viswanathan Mohan, Rinki Murphy, Richard A. Oram, Katharine R. Owen, Susan E. Ozanne, Ewan R. Pearson, Wei Perng, Toni I. Pollin, Rodica Pop‐Busui, Richard E. Pratley, Leanne M. Redman, Rebecca M. Reynolds, Robert K. Semple, Jennifer L. Sherr, Arianne Sweeting, Miriam S. Udler, Kimberly K. Vesco, Tina Vilsbøll, Róbert Wágner, Paul W. Franks

50Citations signalées — pas une note de qualité

162Institutions déclarées

26Pays d’affiliation déclarés

Résumé fourni par la source

BACKGROUND: Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-modifying therapies. METHODS: We systematically reviewed PubMed and EMBASE databases (6/14/2022) assessing 10 years of original research examining relationships between autoantibodies and heterogeneity before, at, after diagnosis, and in response to disease-modifying therapies in individuals at-risk or within 1 year of T1D diagnosis. A critical appraisal checklist tool for cohort studies was modified and used for risk of bias assessment. RESULTS: Here we show that 152 studies that met extraction criteria most commonly characterized heterogeneity before diagnosis (91/152). Autoantibody type/target was most frequently examined, followed by autoantibody number. Recurring themes included correlations of autoantibody number, type, and titers with progression, differing phenotypes based on order of autoantibody seroconversion, and interactions with age and genetics. Only 44% specifically described autoantibody assay standardization program participation. CONCLUSIONS: Current evidence most strongly supports the application of autoantibody features to more precisely define T1D before diagnosis. Our findings support continued use of pre-clinical staging paradigms based on autoantibody number and suggest that additional autoantibody features, particularly in relation to age and genetic risk, could offer more precise stratification. To improve reproducibility and applicability of autoantibody-based precision medicine in T1D, we propose a methods checklist for islet autoantibody-based manuscripts which includes use of precision medicine MeSH terms and participation in autoantibody standardization workshops.

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Contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref: Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
Date Crossref: 06/04/2024
Éditeur: Springer Science and Business Media LLC
Type: journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.

Institutions déclarées

Indiana University School of Medicine Indiana University – Purdue University Indianapolis Baylor College of Medicine Texas Children's Hospital University of Exeter Royal Devon & Exeter NHS Foundation Trust NIHR Exeter Clinical Research Facility Benaroya Research Institute University of Virginia University of South Dakota Sanford Children's Specialty Clinic Richard L. Roudebush VA Medical Center University of Colorado Anschutz Colorado School of Public Health The Royal Melbourne Hospital The University of Melbourne Walter and Eliza Hall Institute of Medical Research Sanford Research Diabetes Australia Brigham and Women's Hospital Harvard University University of Copenhagen Novo Nordisk Foundation Massachusetts General Hospital Lund University University of Cambridge Rosie Hospital University of Calgary Madras Diabetes Research Foundation Cardinal Glennon Children’s Medical Center Saint Louis University Universitat Autònoma de Barcelona Instituto de Salud Carlos III Hospital de Sant Pau Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine Institut de Recerca Sant Pau Broad Institute Johns Hopkins University Johns Hopkins Medicine Rutgers, The State University of New Jersey Centre Hospitalier Universitaire Sainte-Justine Université de Montréal Erasmus MC University of Dundee Genomics (United Kingdom)Stanford University University of Florida University of North Carolina at Chapel Hill University of Helsinki Helsinki University Hospital Institute for Molecular Medicine Finland Folkhälsans Forskningscentrum Boston Children's Hospital Chinese University of Hong Kong University of Malaya Asia Diabetes Foundation Boston Children's Museum University of Eastern Finland Kuopio University Hospital The Queen's Medical Research Institute University of Edinburgh University of Pittsburgh University of Padua Zuyderland Medisch Centrum University of Chicago Deutsches Diabetes-Zentrum e.V.German Center for Diabetes Research Heinrich Heine University Düsseldorf VA Eastern Colorado Health Care System University of Colorado Denver Slovak Academy of Sciences Institute of Experimental Endocrinology of the Slovak Academy of Sciences University of Bergen Haukeland University Hospital Eastern Health Monash University Children's Nutrition Research Center at Baylor College of Medicine University of Manitoba Inserm Sorbonne Université Nutrition et obésité : approches systémiques Assistance Publique – Hôpitaux de Paris Dalian Medical University Second Affiliated Hospital of Chongqing Medical University Chongqing Medical University King's College London University of the Witwatersrand Riley Hospital for Children Institut d'Investigació Biomèdica de Girona Hospital Universitari de Girona Doctor Josep Trueta Northwell Health Feinstein Institute for Medical Research University of California, San Francisco Cedars-Sinai Medical Center The University of Adelaide University of Oxford Oxford Centre for Diabetes, Endocrinology and Metabolism Children's Hospital of Pittsburgh Northwestern University Population Health Research Institute McMaster University University of KwaZulu-Natal University of Minnesota KU Leuven University of Glasgow University of Southern Denmark Rigshospitalet National Health Research Institutes Taipei Veterans General Hospital Taichung Veterans General Hospital Steno Diabetes Centers Aarhus University Hospital University Children's Hospital Tübingen Institute of Diabetes Research Newcastle University Joslin Diabetes Center University Medical Center Groningen Hôpital Saint-Antoine Deakin University Guy's and St Thomas' NHS Foundation Trust Hôpital Necker-Enfants Malades Institut Cochin University of Maryland, Baltimore Dartmouth College Azienda USL di Bologna University of Bologna Pitié-Salpêtrière Hospital National University of Singapore Kaiser Permanente National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Lurie Children's Hospital Impact American Diabetes Association University of Antwerp University of Gondar Trinity College Dublin Wexford General Hospital Endeavor Health Aarhus University University of Washington Université de Sherbrooke Harvard Pilgrim Health Care Seoul National University Hospital Icahn School of Medicine at Mount Sinai Imperial College Healthcare NHS Trust Imperial College London Dr. Mohan's Diabetes Specialities Centre University of Auckland Counties Manukau District Health Board Auckland District Health Board Wellcome/MRC Institute of Metabolic Science Oxford BioMedica (United Kingdom)University of Michigan Translational Research Institute for Metabolism and Diabetes Pennington Biomedical Research Center Institute of Genetics and Cancer Yale University The University of Sydney Royal Prince Alfred Hospital Kaiser Permanente Center for Health Research Düsseldorf University Hospital

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Sujets associés

Diabetes and associated disordersPancreatic function and diabetesT-cell and B-cell Immunology

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