COVID-19 infection among patients with cancer in Australia from 2020 to 2022: a national multicentre cohort study
Rattachement africain : au, cz. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: The global COVID-19 pandemic disproportionately affected certain populations and its management differed between countries. This national study describes characteristics and outcomes of COVID-19 in patients with cancer in Australia. Methods: We performed a multicentre cohort study of patients with cancer and COVID-19 from March 2020 to April 2022. Data were analysed to determine varying characteristics between cancer types and changes in outcomes over time. Multivariable analysis was performed to determine risk factors associated with oxygen requirement. Findings: 620 patients with cancer from 15 hospitals had confirmed COVID-19. There were 314/620 (50.6%) male patients, median age 63.5 years (IQR 50-72) and majority had solid organ tumours (392/620, 63.2%). The rate of COVID-19 vaccination (≥1 dose) was 73.4% (455/620). Time from symptom onset to diagnosis was median 1 day (IQR 0-3), patients with haematological malignancy had a longer duration of test positivity. Over the study period, there was a significant decline in COVID-19 severity. Risk factors associated with oxygen requirement included male sex (OR 2.34, 95% CI 1.30-4.20, p = 0.004), age (OR 1.03, 95% CI 1.01-1.06, p = 0.005); not receiving early outpatient therapy (OR 2.78, 95% CI 1.41-5.50, p = 0.003). Diagnosis during the omicron wave was associated with lower odds of oxygen requirement (OR 0.24, 95% CI 0.13-0.43, p < 0.0001). Interpretation: Outcomes from COVID-19 in patients with cancer in Australia over the pandemic have improved, potentially related to changing viral strain and outpatient therapies. Funding: This study was supported by research funding from MSD.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- COVID-19 infection among patients with cancer in Australia from 2020 to 2022: a national multicentre cohort study
- Date Crossref
- 01/09/2023
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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The University of Melbourne Sir Peter MacCallum Department of Oncology pays non établi dans la noticeUniversité ou école supérieure
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Peter MacCallum Cancer Centre pays non établi dans la noticeÉtablissement de santé
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Lyell McEwin Hospital Department of Oncology pays non établi dans la noticeÉtablissement de santé
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Princess Alexandra Hospital Department of Infectious Diseases pays non établi dans la noticeÉtablissement de santé
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Fiona Stanley Hospital Department of Infectious Diseases pays non établi dans la noticeÉtablissement de santé
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Royal Perth Hospital pays non établi dans la noticeÉtablissement de santé
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Czech Academy of Sciences pays non établi dans la noticeStructure de recherche
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Pathwest Laboratory Medicine Department of Microbiology pays non établi dans la noticeÉtablissement de santé
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Cairns Hospital Department of Cancer Services pays non établi dans la noticeÉtablissement de santé
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Albury Wodonga Health pays non établi dans la noticeÉtablissement de santé
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Royal North Shore Hospital Department of Infectious Diseases pays non établi dans la noticeÉtablissement de santé
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Austin Health pays non établi dans la noticeÉtablissement de santé
Sir Peter MacCallum Department of Oncology — The University of Melbourne, Peter MacCallum Cancer Centre et Department of Oncology — Lyell McEwin Hospital, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.