European e-Delphi process to define expert consensus on electrochemotherapy treatment indications, procedural aspects, and quality indicators in melanoma
Rattachement africain : gb, it, de, pt, ch, si, es, pl, hu. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Skin metastases are an important co-morbidity in melanoma. Despite broad adoption, electrochemotherapy implementation is hindered by a lack of treatment indications, uncertainty regarding procedural aspects, and the absence of quality indicators. An expert consensus may harmonize the approach among centres and facilitate comparison with other therapies. METHODS: An interdisciplinary panel was recruited for a three-round e-Delphi survey. A literature-based 113-item questionnaire was proposed to 160 professionals from 53 European centres. Participants rated each item for relevance and degree of agreement on a five-point Likert scale, and received anonymous controlled feedback to allow revision. The items that reached concordant agreement in two successive iterations were included in the final consensus list. In the third round, quality indicator benchmarks were defined using a real-time Delphi method. RESULTS: The initial working group included 122 respondents, of whom 100 (82 per cent) completed the first round, thus qualifying for inclusion in the expert panel (49 surgeons, 29 dermatologists, 15 medical oncologists, three radiotherapists, two nurse specialists, two clinician scientists). The completion rate was 97 per cent (97 of 100) and 93 per cent (90 of 97) in the second and third rounds respectively. The final consensus list included 54 statements with benchmarks (treatment indications, (37); procedural aspects, (1); quality indicators, (16)). CONCLUSION: An expert panel achieved consensus on the use of electrochemotherapy in melanoma, with a core set of statements providing general direction to electrochemotherapy users to refine indications, align clinical practices, and promote quality assurance programmes and local audits. The residual controversial topics set future research priorities to improve patient care.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- European e-Delphi process to define expert consensus on electrochemotherapy treatment indications, procedural aspects, and quality indicators in melanoma
- Date Crossref
- 03/05/2023
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Manchester University NHS Foundation Trust Department of Surgery pays non établi dans la noticeÉtablissement de santé
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The Christie NHS Foundation Trust Medical Oncology pays non établi dans la noticeOrganisme public
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St George's Hospital Department of Plastic Surgery pays non établi dans la noticeÉtablissement de santé
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Istituto Oncologico Veneto pays non établi dans la noticeÉtablissement de santé
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Azienda Sanitaria di Firenze pays non établi dans la noticeÉtablissement de santé
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Azienda Sanitaria dell'Alto Adige pays non établi dans la noticeÉtablissement de santé
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St. Josef-Hospital pays non établi dans la noticeÉtablissement de santé
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Ruhr University Bochum Department of Dermatology pays non établi dans la noticeUniversité ou école supérieure
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Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" pays non établi dans la noticeÉtablissement de santé
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Instituto Português de Oncologia Francisco Gentil pays non établi dans la noticeÉtablissement de santé
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University of Perugia Department of Surgery and Medicine pays non établi dans la noticeUniversité ou école supérieure
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Ospedale di Bolzano pays non établi dans la noticeÉtablissement de santé
Department of Surgery — Manchester University NHS Foundation Trust, Medical Oncology — The Christie NHS Foundation Trust et Department of Plastic Surgery — St George's Hospital, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.