Figure S2 from Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner
Le résumé fourni par la source
S2.(a) µCT-based monitoring of tumor response in K and KE mice prior to and after cisplatin treatment (left). Quantification of tumor volume in K and KE mice prior to and after cisplatin treatment (right). P values were calculated using two-tailed t-test. (b) Representative immunostaining of Pt-(GpG) adducts in tumor lung sections of KP and KPE mice after single cisplatin treatment (left). Quantification of Pt-(GpG) adduct staining in of KP (n = 3) and KPE mice (n = 4) after single cisplatin treatment (right). P values were calculated using two-tailed t-test. (c) Survival of chemo-naive vs. cisplatin-treated KrasLSL.G12D/wt (K) mice (top left), chemo-naive vs. cisplatin-treated KrasLSL.G12D/wt;Ercc1fl/fl (KE) mice (top right) and comparison of cisplatin-treated KrasLSL.G12D/wt (K) and cisplatin-treated KrasLSL.G12D/wt;Ercc1fl/fl (KE) mice (bottom). P values were calculated using log-rank test.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Figure S2 from <i>Ercc1</i> Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a <i>Tp53</i> Context-Specific Manner
- Date Crossref
- 03/04/2023
- Éditeur
- American Association for Cancer Research (AACR)
- Type
- posted-content
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.