Supplemental Figures and table from KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis

Le résumé fourni par la source

This file contains 6 figures (Supplementary Fig. S1-6) and 1 table (Supplementary Table S1). These figures and table provide additional, directly relevant, and unrepeated information for the article content. In brief, Supplementary Figures S1 and S3 indicate that miR-489 is an effector downstream of KRAS signaling; Supplementary Figures S2 and S5 show that miR-489:ADAM9/MMP7 axis doesn't confer the cell proliferation regulation of KRAS signaling; Supplementary Figure S4 highlights the promoting function of ADAM9 and MMP7 in PDAC metastasis; Supplementary Figure S6 is the additional information of Figure 6 in the main text; and Supplementary Table S1 shows the sequences of chemically synthesized DNA and RNA oligonucleotides. These data are equal in quality and presentation to materials within the main article.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.