Accès ouvert déclaré 2023 article

Effectiveness of nail bed repair in children with or without replacing the fingernail: NINJA multicentre randomized clinical trial

Abhilash Jain, Aina V. H. Greig, Amy Jones, Cushla Cooper, Loretta J Davies, Akiko Greshon, Heidi Fletcher, Adam Sierakowski, Melina Dritsaki, Thi Thu An Nguyen, May Ee Png, Jamie R. Stokes, Helen Dakin, Jonathan Alistair Cook, David John Beard, Matthew D. Gardiner, A Mertic, H Gerrish, K Cranmer, N Fox, P Dutta, G Vissers, P Costa, R Irri, G McArthur, M Horwitz, A Sleiwah, H Jephson, M Deeley, Rebecca Spenser Nicholas, Z Vinnicombe, A Nicola, C Bing Chuo, C Milner, J Heaney, Joshua Philip Totty, Malik Fleet, M Faheem Khadim, P Williams, S Bibawy, A Round, Richard M. Pinder, A Plonczak, G Lawton, D Kennedy, A Bennett, A Fadulelmola, J James, Emma Reay, K Beadon, T Cameron, Z Oliver, K Wensley, S Dupré, J Rodriguez, Dominic Furniss, M Gale, A Knight, J Tulip, L Turner, L Wellings, M Allen, Ryckie George Wade, V Itte, G Bourke, N Kumar, S O'Sullivan, J W M Jones, K Young, Amy M. Taylor, O Dawood, S Booth, L Giwa, R Pearl, Aaron J. Coutts, Rachael Hawkins, Alaa M. Mostafa, T Nisbett, P Riddlestone, A Selby, C Uzoho, D Chasiouras, L. Christopher Bainbridge, Tim Buick, Wilhelmina Lam, Benjamin Baker, K Walsh, K Keating, R Dalan, M Shah, D Mead, S Diment, M Nicolau, B Smeeton, Deric D. Thomson, N Senior, J Moledina, J Colville, K Manso, Myeong Jun Song, O Manley, P Drury, Robert B. Kerstein, W Cobb, Justin C.R. Wormald, R Shirley, A Tan, Angel Arnaout, C Cruz, Naomi Brice, N Segaren, N Joji, Ratandeep Chawla, S Hassanin, R Adami, H Ridha, Aislinn Cook, L Symington, R Long, S Dustagheer, H Jarvis, M Larsen, M Williams, R Trickett, D Miles, A Pai, C Honeywell, C Brady, S Madhavan, V Manou, G Phillips, R Baker

22Citations signalées, ce qui n’est pas une note de qualité

5Institutions déclarées

1Pays d’affiliation déclarés

Rattachement africain : gb. Niveau de preuve : code pays fourni par la source.

Le résumé fourni par la source

BACKGROUND: Surgery for nail bed injuries in children is common. One of the key surgical decisions is whether to replace the nail plate following nail bed repair. The aim of this RCT was to assess the clinical effectiveness and cost-effectiveness of nail bed repair with fingernail replacement/substitution compared with repair without fingernail replacement. METHODS: A two-arm 1 : 1 parallel-group open multicentre superiority RCT was performed across 20 secondary-care hospitals in the UK. The co-primary outcomes were surgical-site infection at around 7 days after surgery and cosmetic appearance summary score at a minimum of 4 months. RESULTS: Some 451 children presenting with a suspected nail bed injury were recruited between July 2018 and July 2019; 224 were allocated to the nail-discarded arm, and 227 to the nail-replaced arm. There was no difference in the number of surgical-site infections at around 7 days between the two interventions or in cosmetic appearance. The mean total healthcare cost over the 4 months after surgery was €84 (95 per cent c.i. 34 to 140) lower for the nail-discarded arm than the nail-replaced arm (P < 0.001). CONCLUSION: After nail bed repair, discarding the fingernail was associated with similar rates of infection and cosmesis ratings as replacement of the finger nail, but was cost saving. Registration number: ISRCTN44551796 (http://www.controlled-trials.com).

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.

Le contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref: Effectiveness of nail bed repair in children with or without replacing the fingernail: NINJA multicentre randomized clinical trial
Date Crossref: 22/03/2023
Éditeur: Oxford University Press (OUP)
Type: journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.

Où se fait cette recherche

Imperial College Healthcare NHS Trust Department of Plastic Surgery pays non établi dans la notice
Établissement de santé
Nuffield Orthopaedic Centre pays non établi dans la notice
Établissement de santé
University of Oxford Rheumatology and Musculoskeletal Sciences pays non établi dans la notice
Université ou école supérieure
Guy's and St Thomas' NHS Foundation Trust Department of Plastic Surgery pays non établi dans la notice
Établissement de santé
Frimley Health NHS Foundation Trust Department of Plastic Surgery pays non établi dans la notice
Établissement de santé
Mid and South Essex NHS Foundation Trust St Andrew’s Centre for Plastic Surgery and Burns pays non établi dans la notice
Organisation à but non lucratif

Department of Plastic Surgery — Imperial College Healthcare NHS Trust, Nuffield Orthopaedic Centre et Rheumatology and Musculoskeletal Sciences — University of Oxford, avec 3 autres affiliations.

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Les sujets associés

Nail Diseases and TreatmentsReconstructive Surgery and Microvascular TechniquesReconstructive Facial Surgery Techniques

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