Molecular Electronic Coupling-Induced Photoacoustics for NIR-I/II Duplex in Vivo Imaging
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Le résumé fourni par la source
Molecular electronic coupling has been found to play a crucial role in the light-induced processes of natural and artificial systems. The light-induced acoustic process (photoacoustic) is also considered to be one of the most essential characters of the light-absorbing molecules. Herein, we report an interesting observation of the molecular electronic coupling-induced photoacoustic effect (MECPA) in which the PA intensity is dominated by the molecular electronic coupling, rather than the absorption intensity as usually concerned. The molecular electronic coupling effect results in a significant exciton absorption suppression from the monomer to pentamer. However, the corresponding PA efficiency was found to be approximately 2 orders of magnitude greater for the latter. A well-behaved linear correlation between the molecular exciton absorbance and PA efficiency was observed. The surprisingly significant MECPA effect was realized via novel NIR-II squaraine-benzothiopyrylium dyes. Excellent photophysical properties of the novel NIR-II dyes were achieved, such as a large absorption extinction coefficient and high photostability. In vivo duplex PA imaging was demonstrated for tumor tissue and macrophage cells and blood and lymphoid vessels. The MECPA effect would open a new window for the design of PA contrast agent systems for in vivo imaging.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Molecular Electronic Coupling-Induced Photoacoustics for NIR-I/II Duplex in Vivo Imaging
- Date Crossref
- 30/01/2023
- Éditeur
- American Chemical Society (ACS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Chinese Academy of Sciences pays non établi dans la noticeOrganisme public
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Shenzhen Institutes of Advanced Technology pays non établi dans la noticeStructure de recherche
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University of Chinese Academy of Sciences pays non établi dans la noticeUniversité ou école supérieure
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Southern University of Science and Technology Department of Chemistry pays non établi dans la noticeUniversité ou école supérieure
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Guangdong Provincial Key Laboratory of Biomedical Optical Imaging Technology and Center for Biomedical Optics and Molecular Imaging pays non établi dans la noticeStructure de recherche
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Guangdong 518131 Shenzhen pays non établi dans la noticeOrganisation à but non lucratif
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Shenzhen College of Advanced Technology pays non établi dans la noticeUniversité ou école supérieure
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Shenzhen Key Laboratory of Nanobiomechanics pays non établi dans la noticeStructure de recherche
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology et University of Chinese Academy of Sciences, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.