War exposure, post-traumatic stress symptoms and hair cortisol concentrations in Syrian refugee children
Rattachement africain : gb, lb, ca. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Altered secretion of cortisol, the primary effector of the hypothalamus-pituitary-adrenal axis, has been proposed as a means by which traumatic experiences compromise later mental health. However, despite the popularity of cortisol as a potential biomarker for stress and adversity, findings are inconsistent, and little is known about the impact of war-related trauma on stress physiology of children and adolescents. Here we aimed to evaluate the relationships between war exposure, current living conditions, hair cortisol concentrations (HCC) and post-traumatic stress disorder (PTSD) symptoms in a large cohort of Syrian refugee children and adolescents (6-18 years) and their caregiver. This longitudinal observational study assessed Syrian refugee children and adolescents in two waves, 1 year apart, within informal tented settlements in Lebanon. The relationships between war exposure, time since leaving Syria, PTSD symptoms and HCC were investigated using linear mixed-model regression utilising both waves of data collected (Y1: N = 1574, Y2: N = 923). Hair cortisol concentration was positively, but weakly associated with the number of war-related events experienced. This was limited to those who were at least 12 years old at the time of war exposure. Conversely, HCC decreased with time since leaving Syria. HCC was also associated with PTSD symptoms but not with the quality of their current living conditions. This study revealed that changes to hypothalamic-pituitary-adrenal axis activity may accompany both earlier war exposure and current PTSD symptoms in children and adolescents. Additionally, early adolescence may be a particularly sensitive time in terms of trauma-related changes to the hypothalamic-pituitary-adrenal axis.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- War exposure, post-traumatic stress symptoms and hair cortisol concentrations in Syrian refugee children
- Date Crossref
- 16/11/2022
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Queen Mary University of London pays non établi dans la noticeUniversité ou école supérieure
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Institute for Development pays non établi dans la noticeOrganisation à but non lucratif
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Western University pays non établi dans la noticeUniversité ou école supérieure
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School of Biological and Behavioural Sciences Department of Biological and Experimental Psychology pays non établi dans la noticeUniversité ou école supérieure
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Balamand University Department of Psychiatry and Clinical Psychology pays non établi dans la noticeUniversité ou école supérieure
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Schulich School of Medicine and Dentistry Department of Physiology and Pharmacology pays non établi dans la noticeUniversité ou école supérieure
Queen Mary University of London, Institute for Development et Western University, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.