Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): recruitment, retention, and data availability in a longitudinal remote measurement study
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Le résumé fourni par la source
BACKGROUND: Major Depressive Disorder (MDD) is prevalent, often chronic, and requires ongoing monitoring of symptoms to track response to treatment and identify early indicators of relapse. Remote Measurement Technologies (RMT) provide an opportunity to transform the measurement and management of MDD, via data collected from inbuilt smartphone sensors and wearable devices alongside app-based questionnaires and tasks. A key question for the field is the extent to which participants can adhere to research protocols and the completeness of data collected. We aimed to describe drop out and data completeness in a naturalistic multimodal longitudinal RMT study, in people with a history of recurrent MDD. We further aimed to determine whether those experiencing a depressive relapse at baseline contributed less complete data. METHODS: Remote Assessment of Disease and Relapse - Major Depressive Disorder (RADAR-MDD) is a multi-centre, prospective observational cohort study conducted as part of the Remote Assessment of Disease and Relapse - Central Nervous System (RADAR-CNS) program. People with a history of MDD were provided with a wrist-worn wearable device, and smartphone apps designed to: a) collect data from smartphone sensors; and b) deliver questionnaires, speech tasks, and cognitive assessments. Participants were followed-up for a minimum of 11 months and maximum of 24 months. RESULTS: Individuals with a history of MDD (n = 623) were enrolled in the study,. We report 80% completion rates for primary outcome assessments across all follow-up timepoints. 79.8% of people participated for the maximum amount of time available and 20.2% withdrew prematurely. We found no evidence of an association between the severity of depression symptoms at baseline and the availability of data. In total, 110 participants had > 50% data available across all data types. CONCLUSIONS: RADAR-MDD is the largest multimodal RMT study in the field of mental health. Here, we have shown that collecting RMT data from a clinical population is feasible. We found comparable levels of data availability in active and passive forms of data collection, demonstrating that both are feasible in this patient group.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): recruitment, retention, and data availability in a longitudinal remote measurement study
- Date Crossref
- 21/02/2022
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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King's College London Institute of Psychiatry pays non établi dans la noticeUniversité ou école supérieure
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Parc Sanitari Sant Joan de Déu pays non établi dans la noticeÉtablissement de santé
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Universitat de Barcelona pays non établi dans la noticeUniversité ou école supérieure
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Amsterdam University Medical Centers pays non établi dans la noticeÉtablissement de santé
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Vrije Universiteit Amsterdam Department of Psychiatry and Amsterdam Public Health Research Institute pays non établi dans la noticeUniversité ou école supérieure
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Lundbeck (Denmark) pays non établi dans la noticeEntreprise
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Centro San Giovanni di Dio Fatebenefratelli pays non établi dans la noticeÉtablissement de santé
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Istituti di Ricovero e Cura a Carattere Scientifico pays non établi dans la noticeÉtablissement de santé
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Janssen (United States) pays non établi dans la noticeEntreprise
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Northwestern University Department of Preventative Medicine pays non établi dans la noticeUniversité ou école supérieure
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Behavioral Tech pays non établi dans la noticeInstitution
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KU Leuven pays non établi dans la noticeUniversité ou école supérieure
Institute of Psychiatry — King's College London, Parc Sanitari Sant Joan de Déu et Universitat de Barcelona, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.