Accès ouvert déclaré
2021
article
Preoperative REM Sleep Behavior Disorder and Subthalamic Nucleus Deep Brain Stimulation Outcome in Parkinson Disease 1 Year After Surgery
Elsa Besse-Pinot, Franck Durif, Maria Livia Fantini, E. Durand, Bérengère Debilly, Philippe Derost, Caroline Moreau, Élodie Hainque, Tiphaine Rouaud, Alexandre Eusébio, Isabelle Bénatru, Sophie Drapier, Dominique Guehl, Olivier Rascol, David Maltête, Ouhaïd Lagha‐Boukbiza, Caroline Giordana, Mélissa Tir, Stéphane Thobois, Lucie Hopes, Cécile Hubsch, Béchir Jarraya, Anne‐Sophie Rolland, Jean‐Christophe Corvol, David Devos, Ana Marquès, Pr. Luc Defebvre, Nicolas Carrière, Guillaume Grolez, Gillaume Baille, Kreisler, Pr. Jean-Pierre Pruvo, Pr. Leclerc, Renaud Lopes, Romain Viard, Grégory Kuchcinski, Mr. Julien Dumont, Pr. Kathy Dujardin, Mme. M Delliaux, Mme. M Brion, Gustavo Touzet, Pr. Nicolas Reyns, Pr. Arnaud Delval, Mme. Valerie Santraine, Mme. Marie Pleuvret, M Dautrevaux, Mr. Victor Laugeais, Thavarak Ouk, Camille Potey, Céline C. Leclercq, Elise Gers, Alain Duhamel, Lynda Djemmane, Florence Duflot, Marie-Vidailhet Jean-Christophe Corvol, Marie‐Laure Welter, Lucette Lacomblez, David Grabli, Emmanuel Roze, Yulia Worbe, Cécile Delorme, Hana You, Jonas Ihle, Raquel Guimeraes-Costa, Florence Cormier‐Dequaire, Aurélie Méneret, Andréas Hartmann, Louise‐Laure Mariani, Stéphane Lehéricy, Virginie Czernecki, Fanny Pineau, Frédérique Bozon, Camille Huiban, Eve Benchetrit, Carine Karachi, Soledad Navarro, Philippe Cornu, Arlette Welaratne, Lise Mantisi, Nathalie Jarry, Sophie Aix, Carine Lefort, Pr. Philippe Damier, Pr. Pascal Derkinderen, Anne-Gaëlle Corbillé, Elisabeth Calvier-Auffray, Laëtitia Rocher, Anne-Laure Deruet, Raoul Sylvie, Roualdes Vincent, Le Dily Séverine, Bérangère Debilly, Pr. Franck Durif, Charlotte Beal, Carine Chassain, Laure Delaby, Tiphaine Vidal, Pr. jean Jeacques Lemaire, Isabelle Rieu, Drapier Sophie, Frédérique Leh, Alexandre Bonnet, Pr. Marc Vérin, Jean‐Christophe Ferré, Jean‐François Houvenaghel, Pr. Claire Haegelen, Françoise Kestens, Solenn ory, Caroline Girodana, Claire Marsé, Lydiane Mondot, Bruno Giordana, Robin Kardous, Bernadette Bailet, H. Joly, Denys Fontaine, Aurélie Leplus, Amélie Faustini, Vanessa Ferrier, Pr Pierre Burbaud, Nathalie Damon‐Perrière, Wassilios G. Meissner, Pr. Francois Tison, Stéphanie Bannier, Elsa Krim, Pr Dominique Guehl, Sandrine Molinier-Blossier, Morgan Ollivier, Marion Lacoste, Nicolas Auzou, Marie Bonnet, Pr. Emmanuel Cuny, Julien Engelhardt, Olivier Branchard, Clotilde Huet, Julie Blanchard, Pr. Alexandre Eusebio, Pr. Jean-Philippe Azulay, Tatiana Witjas, Frédérique Fluchère, Stéphan Grimaldi, P Girard, Marie Delfini, Romain Carron, Pr. Jean Regis, Giorgio Spatola, Camille Magnaudet, Ansquer Solène, Benatru Isabelle, Colin Olivier, Pr. Houeto Jean Luc, Pr. Guillevin Remy, Fradet Anne, Anziza Manssouri, Blondeau Sophie, Richard Philippe, C Rott Philippe, Page Philippe, Pr. Bataille Benoit, Rabois Emilie, Guillemain Annie, Pr. David Maltete, Romain Lefaucheur, Damien Fetter, Nicolas Magné, Sandrine Bioux, Maud Loubeyre, Evangéline Bliaux, Dorothée Pouliquen, Pr. Stéphane Derrey, Mme. Linda Vernon, Frédéric Ziegler, Pr. Rascol Olivier, Christine Brefel Courbon, Fabienne Ory Magne, Marion Simonetta Moreau, Pr. Christophe Arbus, Pr Fabrice Bonneville, Jean Albert Lotterie, Marion Sarrail, Pr. Patrick Chaynes, Pr. François Caire, Estelle Harroch, Pr. Mathieu Anheim, Pr. Christine Tranchant, Odile Gebus, Solveig Montaut, Stéphane Kremer, Nadine Longato, Clélie Phillips, Jimmy Voirin, Marie des Neiges Santin, Dominique Chaussemy, Amaury C. Mengin, Pr. Pierre Krystkowiak, P Constans, Sandrine Wannepain, Audrey Seling, Michel Lefranc, Stéphanie Blin, Béatrice Schuler, Pr. Stephane Thobois, Téodor Danaila, Chloé Laurencin, P. Berthézène, Roxana Améli, Hélène Klinger, Gustavo Polo, Émile Simon, Patrick Mertens, Abraham Nunes, Élise Météreau, Emmanuelle Schmitt, Mylène Meyer, Céline Dillier, Pr. Sophie Colnat, Anne Chatelain, Jean- Philippe Brandel, Patte Karsenti, Marie Lebouteux, Marc Ziégler, Christine Delmaire, Julien Savatowky, Juliette Vrillac, Claire Nakache, Vincent d’Hardemare, Lhaouas Belamri, Frédérique Bourdain, Vadim Afanassiev, Philippe Graveleau, Camille Decrocq, Anne Boulin, V Elodie Dupuy, Bérénice Gardel, Pr. Béchir Jarraya, Delphine Lopez, Christophe Fruit, David Gay, Robin Bonice, Fouzia El Mountassir, Clara Fischer, Jean‐François Mangin, Marie Chupin, Yann Cointepas, Bertrand Accart, Patrick Gelé, Florine Fievet, Matthieu Chabel, Virginie Derenaucourt, Loïc Facon, Yanick Tchantchou Njosse, Dominique Deplanque
6Citations signalées — pas une note de qualité
23Institutions déclarées
3Pays d’affiliation déclarés
Résumé fourni par la source
Background and Objectives To determine whether patients with Parkinson disease (PD) eligible for subthalamic nucleus deep brain stimulation (STN-DBS) with probable REM sleep behavior disorder (RBD) preoperatively could be more at risk of poorer motor, nonmotor, and quality of life outcomes 12 months after surgery compared to those without RBD. Methods We analyzed the preoperative clinical profile of 448 patients with PD from a French multicentric prospective study (PREDISTIM) according to the presence or absence of probable RBD based on the RBD Single Question and RBD Screening Questionnaire. Among the 215 patients with PD with 12 months of follow-up after STN-DBS, we compared motor, cognitive, psycho-behavioral profile, and quality of life outcomes in patients with (pre-opRBD+) or without (pre-opRBD–) probable RBD preoperatively. Results At preoperative evaluation, pre-opRBD+ patients were older (61 ± 7.2 vs 59.5 ± 7.7 years; p = 0.02), had less motor impairment (Movement Disorder Society–sponsored version of the Unified Parkinson’s Disease Rating Scale [MDS-UPDRS] III “off”: 38.7 ± 16.2 vs 43.4 ± 7.1; p = 0.03) but more nonmotor symptoms on daily living activities (MDS-UPDRS I: 12.6 ± 5.5 vs 10.7 ± 5.3; p < 0.001), had more psychobehavioral manifestations (Ardouin Scale of Behavior in Parkinson9s Disease total: 7.7 ± 5.1 vs 5.1 ± 0.4; p = 0.003), and had worse quality of life (Parkinson9s Disease Questionnaire–39: 33 ± 12 vs 29 ± 12; p = 0.03), as compared to pre-opRBD– patients. Both pre-opRBD+ and pre-opRBD– patients had significant MDS-UPDRS IV score decrease (−37% and −33%, respectively), MDS-UPDRS III “med ‘off’/stim ‘on’” score decrease (−52% and −54%), and dopaminergic treatment decrease (−52% and −49%) after surgery, with no between-group difference. There was no between-group difference for cognitive and global quality of life outcomes. Conclusions In patients with PD eligible for STN-DBS, the presence of probable RBD preoperatively is not associated with a different clinical outcome 1 year after neurosurgery. Trial Registration Information NCT02360683. Classification of Evidence This study provides Class II evidence that in patients with PD eligible for STN-DBS, the presence of probable RBD preoperatively is not associated with poorer outcomes 1 year post surgery.
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Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Preoperative REM Sleep Behavior Disorder and Subthalamic Nucleus Deep Brain Stimulation Outcome in Parkinson Disease 1 Year After Surgery
- Date Crossref
- 16/11/2021
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Sujets associés
Neurological disorders and treatmentsParkinson's Disease Mechanisms and TreatmentsRestless Legs Syndrome Research