Compound’s Pre-Screening of Withania somnifera, Bacopa monnieri and Centella asiatica Extracts
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Le résumé fourni par la source
Spectral fluorescence signature, Gas Chromatography-Mass Spectrometry and Liquid Chromatography-Mass Spectrometry for identification of chemical and bioactive compounds were applied to study the plant extracts of Withania somnifera, Centella asiatica and Bacopa monnieri which are related to the possible treatment of mental diseases as Alzheimer, Parkinson and Depression. These plants are known for different positive phytotherapeutic effects on the human brain without negative post-, adverse or after effects to the treated individuals, and have been recommended in several medical studies. Therefore, we selected these plants for further analysis, based on the inhibition results of in vitro Amyloid Beta fibrillation tests made by previous measurements. With this study a first screening of the complex plant extract mixtures was performed, to get an initial overview about known and unknown ingredients. In all three plants, similar main compounds were identified, however in different quality and quantity. These may provide substantial information on which compound combinations might be mainly responsible for the positive effects and should be further investigated being responsible for reducing the fibrillation process of Amyloid Beta.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Compound’s Pre-Screening of <i>Withania somnifera</i>, <i>Bacopa monnieri</i> and <i>Centella asiatica</i> Extracts
- Date Crossref
- 01/01/2020
- Éditeur
- Scientific Research Publishing, Inc.
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Tallinn University of Technology Department of Chemistry and Biotechnology pays non établi dans la noticeUniversité ou école supérieure
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Karlsruhe Institute of Technology pays non établi dans la noticeUniversité ou école supérieure
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Center for Integrated Quantum Science and Technology pays non établi dans la noticeStructure de recherche
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Competence Center of Food and Fermentation Technology (TFTAK) pays non établi dans la noticeInstitution
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Ulm University Institute for Quantum Optics pays non établi dans la noticeUniversité ou école supérieure
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Institute of Nanotechnology pays non établi dans la noticeStructure de recherche
Department of Chemistry and Biotechnology — Tallinn University of Technology, Karlsruhe Institute of Technology et Center for Integrated Quantum Science and Technology, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.