Repositioning of the global epicentre of non-optimal cholesterol
301Citations signalées — pas une note de qualité
405Institutions déclarées
93Pays d’affiliation déclarés
Résumé fourni par la source
Abstract High blood cholesterol is typically considered a feature of wealthy western countries 1,2 . However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world 3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health 4,5 . However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.
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Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Repositioning of the global epicentre of non-optimal cholesterol
- Date Crossref
- 03/06/2020
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Institutions déclarées
Imperial College LondonHarvard UniversityUniversity of AucklandTehran University of Medical SciencesMiddlesex University LondonShahid Beheshti University of Medical SciencesRush University Medical CenterInstituto de Efectividad Clínica y SanitariaErasmus MCWorld Health OrganizationFilm IndependentUniversity of California, BerkeleyMahidol UniversityCharles UniversityThomayer University HospitalIstituto Superiore di SanitàSouth African Medical Research CouncilSeoul National UniversityFinnish Institute for Health and WelfareNational Institute of NutritionPontificia Universidad Católica de ChileNational Centre for Disease Informatics and ResearchCopenhagen University HospitalCapital Medical UniversityBeijing Anzhen HospitalFrederiksberg HospitalCosta Rican Department of Social SecurityQatar UniversityBirzeit UniversityMexican Social Security InstituteFlinders UniversityNutrition Center of the PhilippinesUrmia UniversityUrmia University of Medical SciencesInstituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránUniversity of AmsterdamSteno Diabetes CentersMinistry of HealthShahrekord University of Medical SciencesUniversity of OsloUniversity of BremenDasman Diabetes InstituteKing Abdullah International Medical Research CenterLuxembourg Institute of HealthWorld Health Organization Regional Office for the Eastern MediterraneanBombay HospitalUniversité de LilleWestern Norway University of Applied SciencesVestlandsforskingNorwegian School of Sport SciencesMadras Diabetes Research FoundationZahedan University of Medical SciencesNational Heritage InstituteUniversidade do PortoNorwegian Institute of Public HealthUniversity of Massachusetts AmherstAbt Associates (Nepal)University of IcelandUniversidade Federal de PelotasOulu University HospitalUniversity of OuluPublic Health Authority of the Slovak RepublicResearch Institute for Endocrine SciencesUniversity of Science and TechnologyMedical University of LodzGdańsk Medical UniversityCentro de Investigación Biomédica en Red de Epidemiología y Salud PúblicaUniversidad Autónoma de MadridUniversity of PalermoWorld Health Organization Regional Office for the AmericasMohammed V UniversityDalhousie UniversityJordan University of Science and TechnologyAl-Farabi Kazakh National UniversityThe University of SydneyChristian Medical College, VelloreTunis El Manar UniversityFundación Universitaria CafamKazakh National Medical UniversityUniversidad Peruana Cayetano HerediaLithuanian University of Health SciencesUniversidade de São PauloSunder Lal Jain HospitalJain hospitalShanghai Jiao Tong UniversityPublic Health Agency of CanadaUfa Eye Research InstituteNepal Health Research CouncilUniversity of Southern DenmarkUniversity of GothenburgUniversidade Federal do Rio de JaneiroNational Institute for Public Health and the EnvironmentUniversity of TurinNanyang Technological UniversityUniversidad de la República de UruguayCentro de Educación Médica e Investigaciones Clínicas Norberto QuirnoIstituto Neurologico MediterraneoFondazione Audiologica VareseKU LeuvenMinistry of HealthUniversity of LausanneCentral University of VenezuelaBielefeld UniversityGerman Cancer Research CenterHeidelberg UniversityUniversity College CopenhagenRobert Koch InstituteUniversidad de La LagunaUniversity of MaltaIstanbul University-CerrahpaşaUniversidade Federal de Juiz de ForaUniversidade de Santiago de CompostelaCereal Research CentreDr. A. Ramachandran's Diabetes HospitalsUniversity College LondonAcademia SinicaCapital Institute of PediatricsKailuan General HospitalDuke-NUS Medical SchoolAhvaz Jundishapur University of Medical SciencesIsrael National Institute for Health Policy ResearchMinistry of Health and WelfareKorea Disease Control and Prevention AgencyKorea Center for Disease Control and PreventionMedical University of SilesiaStatistics CanadaGhent University HospitalUniversidade Federal do MaranhãoUniversity of SouthamptonInstitut Pasteur de LilleSpanish Biomedical Research Centre in Physiopathology of Obesity and NutritionUniversity of DebrecenUniversidade Federal do Rio Grande do SulUniversidade Federal de Santa CatarinaEduardo Mondlane UniversityUniversity Hospital of GenevaNational Research Center for Preventive MedicineUniversité de MontréalSanté Publique FranceClinica MediterraneaUniversity of ZagrebMinistry of Health and Medical EducationThe University of QueenslandUniversity of CuencaHelmholtz MunichCarol Davila University of Medicine and PharmacyDüsseldorf University HospitalHeinrich Heine University DüsseldorfInstitute of CardiologyBeth Israel Deaconess Medical CenterUniversity of LatviaHormozgan University of Medical SciencesUniversity of SkövdeInstitut National de Nutrition et de Technologie AlimentaireUniversity of the West IndiesHospital del Mar Research InstituteStellenbosch UniversityUniversity of Duisburg-EssenKaradeniz Technical UniversityUniversity of HelsinkiMashhad University of Medical SciencesRafsanjan University of Medical SciencesQueen's University BelfastUniversity of ZurichTabriz University of Medical SciencesFasa University of Medical SciencesShiraz University of Medical SciencesCentro de Implantología Cirugía Oral y MaxilofacialServicio Aragonés de SaludHospital Universiti Sains MalaysiaUmeå UniversityUniversidade Federal de São PauloHospital Universitario Son EspasesKindai UniversityKyoto UniversityMedical University of WarsawUniversity of CataniaUniversidade Federal de Minas GeraisWageningen University & ResearchB.P. Koirala Institute of Health SciencesUniversity of InsubriaThe University of AdelaideLund UniversityMcGill UniversityUniversidad Politécnica de MadridUniversity Hospital BrnoSt. Anne's University Hospital BrnoInstituto Nacional de Salud PúblicaUniversidad MaristaUniversidad Autónoma de Santo DomingoInstitute of Clinical and Experimental MedicineJagiellonian UniversityNational Clinical Research Center for Digestive DiseasesSingapore Eye Research InstituteIcelandic Heart AssociationIcesi UniversityEternal HospitalNational Health Insurance ServiceUniversity of the West IndiesKermanshah University of Medical SciencesUniversity of Eastern FinlandKyushu UniversityUniversity of BergenTulane UniversityChinese Center For Disease Control and PreventionJoep Lange InstituteChinese University of Hong KongUniversity of Hong KongThe University of Western AustraliaKingston Health Sciences CentreFoscal HospitalMinistry of Health and SportsAmsterdam UMC Location Vrije Universiteit AmsterdamCentre international de recherche sur le cancerAmerican University of BeirutCairo UniversityUniversidad de ZaragozaNational Institute of Biomedical Innovation, Health and NutritionMedical University of VarnaThe University of TokyoHospital for Sick ChildrenNiigata UniversityHadassah Medical CenterNorwegian University of Science and TechnologyThe University of MelbourneUniversity Hospital Centre ZagrebNational Heart Foundation of AustraliaTwelfth Guangzhou City People's HospitalUniversidad Eugenio María de HostosSimon Fraser UniversityWorld Health Organization - IndiaGuilan University of Medical SciencesUniversity of OpoleUniversity of CreteNational University of MalaysiaMaharajgunj Medical CampusJohns Hopkins UniversityNational Institute of EpidemiologyUniversity of MünsterKyrgyz State Medical AcademyForschungsinstitut für KinderernährungMazandaran University of Medical SciencesInnsbruck Medical UniversityUniversität InnsbruckMuhimbili University of Health and Allied SciencesYonsei UniversityNational Cancer CenterUniversity of PennsylvaniaUniversity of ViennaOulu Deaconess InstituteTartu University HospitalKansai Medical UniversityMinistry of Health and Quality of LifeUniversity Hospital UlmUniversity of GroningenUniversity of JyväskyläAfrican Population and Health Research CenterHarokopio University of AthensUniversity of Public Health YangonNational University of SingaporeTampere UniversityTampere University HospitalTampere UniversityUniversity of Cape TownWest Virginia UniversityFundação Oswaldo CruzNational Taiwan UniversityUniversity of Chinese Academy of SciencesUppsala UniversityNational Institute for Health DevelopmentUniversidad de San Martín de PorresJunta de Castilla y LeónVästerbotten CountyPeking UniversityUniversidade Federal de Ouro PretoUniversity of CoimbraJikei University School of MedicineNational Research CouncilBaker Heart and Diabetes InstituteAgricultural University of AthensHospital Israelita Albert EinsteinUniversity of OtagoUniversity of PaduaEmory UniversityUniversidade Estadual do Centro-OesteUiT The Arctic University of NorwayCape Peninsula University of TechnologyBrown UniversityUniversity of EdinburghUniversity College DublinShahid Sadoughi University of Medical Sciences and Health ServicesInsermNational Institute of Medical StatisticsUniversidade LusófonaUniversity of FlorenceAin Shams UniversityUniversité de StrasbourgUniversity of PecsMulago HospitalUniversidad de Ciencias Médicas de CienfuegosRoyal College of Surgeons in IrelandLa Trobe UniversityInternational Institute of Molecular and Cell BiologyInstituto Conmemorativo Gorgas de Estudios de la SaludWorld Health Organization - MalawiUniversity of BresciaBushehr University of Medical SciencesUniversität UlmKobe UniversitySuraj Eye InstituteUniversitätsmedizin GreifswaldUniversity of Medicine and Pharmacy at Ho Chi Minh CityHanoi Medical UniversityMiami VA Healthcare SystemUniversity of TurkuEastern Mediterranean Public Health NetworkUniversity of ManchesterJapan Wildlife Research CenterIstanbul UniversityMinistry of HealthUniversidade da MadeiraMRC Lifecourse Epidemiology UnitUniversity of Novi SadKwame Nkrumah University of Science and TechnologyGastroenterology Hospital "Saverio de Bellis"Centro de Medicina Avanzada Dr. Abel GonzalezLeibniz Institute for Prevention Research and Epidemiology - BIPSUniversity of SarajevoInstituto de Salud de BucaramangaArdabil University of Medical SciencesJahrom University of Medical SciencesAlborz University of Medical SciencesMinistry of HealthIndia Diabetes Research FoundationInstitut Universitari d'Investigació en Atenció Primària Jordi GolUniversiti Putra MalaysiaUniversity of MalayaUniversitat de ValènciaUniversity of the Philippines ManilaFundació Balear d'Innovació i TecnologiaAmsterdam Institute for Global Health and DevelopmentServicio Canario de la SaludIndustrial University of SantanderAssociazione Calabrese di EpatologiaSahlgrenska University HospitalUniversité Fédérale de Toulouse Midi-PyrénéesInstitute of Food ScienceSitaram Bhartia Institute of Science and ResearchFaculté de médecine de TunisNational Institute of QualityCatalan Society of Family and Community MedicineUniversity of LisbonLusíada University of LisbonEtelä-Karjalan sosiaali ja terveyspiiriHospital São PauloHospital Italiano de Buenos AiresKing's College LondonNational Center for Global Health and MedicineSungkyunkwan UniversityFinnish Institute of Occupational HealthSt Vincent's Hospital SydneyUNSW SydneyKarolinska InstitutetLondon School of Hygiene & Tropical MedicineDiponegoro UniversityUniversity of Bari Aldo MoroUniversity of CopenhagenInstitut Régional de Santé PubliqueUniversité de BordeauxIzmir Kâtip Çelebi UniversityUniversity of BonnHrvatski zavod za javno zdravstvoNarodowy Instytut Zdrowia Publicznego PZH – Państwowy Instytut BadawczyFu Jen Catholic UniversityInstituto Nacional de EstatísticaMinistry of HealthCentral University of KeralaHealth Research Institute of the Balearic IslandsUniversidad Centroccidental Lisandro AlvaradoDokuz Eylül UniversityIcahn School of Medicine at Mount SinaiUtrecht UniversityHanoi UniversityUniversity Medical Center UtrechtUniversity of IndonesiaInstituto de investigación sanitaria y biomédica de AlicanteNorth Karelia Central HospitalUniversity of the WitwatersrandMunster Technological UniversityInstitute for Medical ResearchHealth CanadaBeijing Institute of NeurosurgeryXinjiang Medical UniversitySt George's, University of LondonMedical University of ViennaUniversity of OxfordMinistry of Agriculture and Rural AffairsChildren's Hospital of Fudan UniversityRCSI & UCD Malaysia CampusUniversity of CyprusIran University of Medical SciencesJiangsu Provincial Center for Disease Control and PreventionSun Yat-sen UniversityWest Kazakhstan Marat Ospanov State Medical UniversityUniversity of Ghana
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