Predictors with regard to ingestion, inhalation and dermal absorption of estimated phthalate daily intakes in pregnant women: The Barwon infant study
Rattachement africain : nl, au. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Human exposure to phthalate chemicals, used in consumer product plastics, occurs throughout the day. Phthalate levels in pregnant women are associated with offspring health effects including obesity and neurodevelopmental problems. Knowledge of predictors of exposure is necessary in order to effectively reduce phthalate exposure. The present study aims to identify predictors of phthalate levels in Australian pregnant women from the Barwon Infant study birth cohort. Maternal urine samples from 841 women were analyzed for phthalate metabolites. Maternal diet and food preparation practices, use of volatile household products, household characteristics and personal care product use were assessed with questionnaires. All maternal urine contained phthalate metabolites. Maternal prenatal high-fat milk consumption was associated with higher benzyl butyl phthalate (BBzP) (p < 0.001), and bis(2-ethylhexyl) phthalate (DEHP) (p = 0.0023). Higher phthalate levels were associated with consumption of tinned food (fish and tomatoes). Diethyl phthalate (DEP) levels were significantly higher when women reported using air freshener (35% increase, p = 0.01), aerosols (40% increase, p = 0.005), hair treatment chemicals (28% increase, p = 0.031), and chlorine (34% increase, p = 0.009) compared to no use. Maternal phthalate levels did not vary by reported plastic avoidance during pregnancy. The study showed that phthalate exposure is ubiquitous and increased by multiple factors. Future intervention studies to reduce phthalate levels among pregnant women will need to take into account the variety of sources identified in this study.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Predictors with regard to ingestion, inhalation and dermal absorption of estimated phthalate daily intakes in pregnant women: The Barwon infant study
- Date Crossref
- 01/06/2020
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Vrije Universiteit Amsterdam Department of Environment and Health pays non établi dans la noticeUniversité ou école supérieure
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Royal Children's Hospital pays non établi dans la noticeÉtablissement de santé
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Murdoch Children's Research Institute pays non établi dans la noticeOrganisation à but non lucratif
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Deakin University pays non établi dans la noticeUniversité ou école supérieure
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Barwon Health pays non établi dans la noticeÉtablissement de santé
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Geelong Hospital Barwon Health pays non établi dans la noticeÉtablissement de santé
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Victorian Clinical Genetics Services pays non établi dans la noticeStructure de recherche
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The University of Queensland Child Health Research Centre pays non établi dans la noticeUniversité ou école supérieure
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Florey Institute of Neuroscience and Mental Health pays non établi dans la noticeStructure de recherche
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University of Melbourne Murdoch Children's Research Institute pays non établi dans la noticeUniversité ou école supérieure
Department of Environment and Health — Vrije Universiteit Amsterdam, Royal Children's Hospital et Murdoch Children's Research Institute, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.