Jochen F. Mueller

Trends of Nonylphenol Exposure in an Australian Population Based on Urinary Metabolite Analysis

Danielle E. Que, Katharina E. Ebert, Ian Zammit, Benedikt Ringbeck et autres

Abstract Nonylphenol (NP) is an alkylphenol primarily used to synthesize nonylphenol ethoxylates (NPEO) and tris(4-nonylphenyl) phosphite (TNPP) which are extensively used in industrial and consumer products. NP and its derivatives are well-known endocrine disruptors and are associated with other toxic effects, raising …

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Assessing UV Filter Exposure in Queensland, Australia: Human Biomonitoring Evidence Highlighting Homosalate in Children

Katharina E. Ebert, Danielle E. Que, Anne Lotz, Thomas Brüning et autres

Abstract Sunscreens are an important protection measure against harmful effects of ultraviolet radiation. However, potential health effects of several commonly used UV filters are currently being discussed. We conducted a human biomonitoring (HBM)-based exposure and risk assessment for octocrylene (OC), 2-ethylhexyl salicylate …

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Validation of a method for quantification of bisphenols and phthalate metabolites in post-mortem human brain tissue

Ian Zammit, Ayomi Jayarathne, Emerson Aldridge, Eurwin Suryana et autres

The cost-effectiveness and versatility of plastics have made them ubiquitous, leading to widespread human exposure to plastic associated chemicals like phthalates and bisphenols. While these chemicals are linked to adverse health effects, including hormonal and neurobehavioral, their bioavailability to the brain remains …

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Predictors of bisphenol A exposure in pregnant women of the Barwon Infant Study

Eva J. Sugeng, Sarah Thomson, James Hedley, Martin O’Hely et autres

Bisphenol-A (BPA) is a widely used chemical used in plastic and an endocrine disruptor ubiquitous in most developed settings. Exposure, particularly in early life, is implicated in a range of negative health outcomes. This study assessed whether various sources of BPA exposure …

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Does the presence of polychlorinated alkanes in plastic fruit stickers adhesive pose a threat to human health?

Chang He, Sebastian Zellmer, Walter Vetter, 李桂英 et autres

Polychlorinated alkanes (PCAs) are widely used in products as adhesives. While the environmental and human health risks of PCAs are increasingly recognized, little attention has been paid to their presence in food-contact materials such as fruit stickers. This study represents the first …

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Predictors of bisphenol A exposure in pregnant women of the Barwon Infant Study

Eva J. Sugeng, Sarah Thomson, James Hedley, Martin O’Hely et autres

Bisphenol-A (BPA) is a widely used chemical used in plastic and an endocrine disruptor ubiquitous in most developed settings. Exposure, particularly in early life, is implicated in a range of negative health outcomes. This study assessed whether various sources of BPA exposure …

Monitoring ketamine use and evaluating its persistence across 106 wastewater treatment plants in Australia

Zeyang Zhao, Rory Verhagen, Jake W. O'Brien, Benjamin J. Tscharke et autres

Ketamine, commonly used for anaesthesia, has seen increasing recreational use worldwide. In this study, we aimed to (i) assess ketamine use across different regions in Australia, and (ii) evaluate ketamine removal during wastewater treatment processes and the associated ecological risks. Wastewater samples …

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Trends of Fentanyl and Oxycodone Use in Australia (2018–2022) in National Prescription and Wastewater Data Sets

Hieu K.T. Ngo, Phong Khanh Thai, Jason P. Connor, B J Loveday et autres

Triangulating complementary data sources can provide a more complete picture of population-level opioid use trends, both spatially and temporally. This study aimed to evaluate trends in fentanyl and oxycodone use in Australia from 2018 to 2022 using two data sources: Pharmaceutical Benefits …

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Exploratory Study on Plasticiser Intake During Intermittent Fasting: Effects on Weight, Glycaemic Control and Vitamin D Levels in Type 2 Diabetes

Edwina Brennan, Priya Das, Pearl Wasif, Xianyu F. Wang et autres

Introduction: Intermittent fasting (IF) is becoming increasingly popular as a method of weight management, but it is unknown whether it affects plasticiser intake with resultant changes in glycaemic control in diabetes and vitamin D (VitD) levels; therefore, this study was undertaken in …

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Impact of nano zero valent iron dosing on biotransformation and adsorption of 20 biomarkers in sewers

Jianan Ren, Xiaotong Cen, Jiaying Li, Pritesh Prasad et autres

Understanding the stability of biomarkers during sewer transport is one of the crucial steps when applying wastewater-based epidemiology (WBE) for assessing consumption or exposure to chemicals. Their stability could be impacted by chemical dosing, a common method used to control the generation …

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Biodegradation Rates of Organic Chemicals in a Subtropical River: From Laboratory to Field

Lily M. Weir, Run Tian, Malte Posselt, Jochen F. Mueller et autres

High Resolution Image Download MS PowerPoint Slide Understanding the attenuation rate of organic chemicals in aquatic environments is essential for assessing their long-term ecological risks and informing chemical management. Biodegradation is a key attenuation pathway for many chemicals, however, measuring biodegradation in …

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Monitoring Population Exposure to Low‐ and No‐Calorie Sweeteners via Pooled Urine Analysis

Nicole S. Schröter, Jake William O'Brien, Richard Bade, Leisa-Maree L. Toms et autres

ABSTRACT Low‐ and no‐calorie sweeteners (LNCS) are increasingly used as sugar substitutes in processed foods and sweetened beverages to reduce energy intake while maintaining taste. Given that poor diet remains a major contributor to non‐communicable diseases, LNCS offer a strategy to lower …

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