A Portable System to Monitor Saliva Conductivity for Dehydration Diagnosis and Kidney Healthcare
Rattachement africain : tw. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Chronic kidney disease (CKD) has become a major issue in long-term healthcare. It is caused by recurrent kidney injury, which is possible induced by dehydration and heat stress. Therefore, it is important to access the dehydration diagnosis on fields. Conventional instruments for assessing dehydration from blood and urine samples are expensive and time-consuming. These disadvantages limit their applications in high-risk groups susceptible to kidney disease. To address this unmet need, this study presents a portable miniaturized device for dehydration diagnosis with clinical saliva samples. With co-plane coating-free gold electrodes, the dehydration diagnosis was achieved with a saliva specimen at low volumes (50-500 μL). To examine the characteristics, the developed device was assessed by using standard conductivity solutions and the examined variation was <5%. To validate the use for field applications, saliva samples were measured by the developed device and the measured results were compared with standard markers of serum osmolality (N = 30). These data indicate that the measured saliva conductivity is consistent with serum osmolality. And it shows significant difference between healthy adults and healthy farmers (p < 0.05), who typically suffer high risks of CKD. Based on this work, the proposed device and measurement offer a useful method to diagnosis dehydrations and indicate possible potential for CKD.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A Portable System to Monitor Saliva Conductivity for Dehydration Diagnosis and Kidney Healthcare
- Date Crossref
- 14/10/2019
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Institutes of Applied Research pays non établi dans la noticeOrganisme public
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Chiayi Chang Gung Memorial Hospital Department of Neurosurgery pays non établi dans la noticeÉtablissement de santé
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Chang Gung University pays non établi dans la noticeUniversité ou école supérieure
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Chang Gung Memorial Hospital pays non établi dans la noticeÉtablissement de santé
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National Taiwan University Graduate Institute of Electrical Engineering pays non établi dans la noticeUniversité ou école supérieure
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National Taipei University pays non établi dans la noticeUniversité ou école supérieure
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Taiwan Instrument Research Institute pays non établi dans la noticeStructure de recherche
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College of Medicine pays non établi dans la noticeUniversité ou école supérieure
National Institutes of Applied Research, Department of Neurosurgery — Chiayi Chang Gung Memorial Hospital et Chang Gung University, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.