Prophylaxis of Non-communicable Diseases: Why Fruits and Vegetables may be Better Chemopreventive Agents than Dietary Supplements Based on Isolated Phytochemicals?
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Le résumé fourni par la source
The World Health Organization (WHO) report from 2014 documented that non-communicable socalled civilization diseases such as cardiovascular disease, chronic respiratory diseases, cancer or type 2 diabetes are responsible for over 50% of all premature deaths in the world. Research carried out over the past 20 years has provided data suggesting that diet is an essential factor influencing the risk of development of these diseases. The increasing knowledge on chemopreventive properties of certain food ingredients, in particular, those of plant origin, opened the discussion on the possibility to use edible plants or their active components in the prevention of these chronic diseases. Health-promoting properties of plant foods are associated with the presence of secondary metabolites that can affect many biological mechanisms of critical importance to the proper functioning of the human organism. Particularly, there have been numerous investigations indicating strong physiological effects of bioactive plant phenols belonging to the flavonoid family. These observations initiated mass production of dietary supplements containing flavonoids commercialized under the name antioxidants, even if their chemical properties did not justify such a term. However, epidemiological studies revealed that isolated bioactive phytochemicals are not as effective as fruits and vegetables containing these substances whereas they are of interest of the functional food industry. In this paper, the critical assessment of reasons for this turn of events has been attempted and the concept of food synergy has been suggested as a future strategy of dietary chemoprevention.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Prophylaxis of Non-communicable Diseases: Why Fruits and Vegetables may be Better Chemopreventive Agents than Dietary Supplements Based on Isolated Phytochemicals?
- Date Crossref
- 23/08/2019
- Éditeur
- Bentham Science Publishers Ltd.
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Gdańsk University of Technology pays non établi dans la noticeUniversité ou école supérieure
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University of Belgrade pays non établi dans la noticeUniversité ou école supérieure
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University of Milano-Bicocca Department of Medicine and Surgery pays non établi dans la noticeUniversité ou école supérieure
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Stazione Zoologica Anton Dohrn pays non établi dans la noticeStructure de recherche
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Université de Bourgogne BioPeroxIL Laboratory pays non établi dans la noticeUniversité ou école supérieure
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University of Insubria pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Chemistry Department of Food Chemistry pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Pharmacy Department of Bromatology pays non établi dans la noticeUniversité ou école supérieure
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Universita degli Studi dell'Insubria pays non établi dans la noticeInstitution
Gdańsk University of Technology, University of Belgrade et Department of Medicine and Surgery — University of Milano-Bicocca, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.