Circadian Variation in Stroke-Reply

Le résumé fourni par la source

In Reply. —We appreciate Dr Alberts' concerns about the potential shortcomings in determining the time of onset. This is clearly an inherent problem in all clinical studies and trials that depend on a patient's or family's recollection and ability to accurately communicate a history. In our study, considerable time and effort were devoted to circumvent this problem at the level of data collection and in our subsequent analysis. Time of onset was determined from the patient and/or the family at the time of initial evaluation by the study neurologist (within 24 hours of onset). In addition, they were asked specifically if symptoms had first been noted on In the data analysis, patients who had noted on awakening and those whose time of onset had been estimated to occur at the time of awakening were included in the category of stroke on awakening. Twenty-nine patients

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.