Shenyang Maternity and Child Health Hospital

Comparative Therapeutic Strategies for Secondary Progressive Multiple Sclerosis: A Systematic Review and Network Meta-Analysis

Ye Yin, Jia Gao, Danyu Zhao

cn, us (code pays fourni par la source)

WTAP Dysregulation Mediates HLF ‐ m6A Modification to Inhibit Trophoblast Ferroptosis in Preeclampsia

Shuang Liu, Li Zhang, Yan Li, Jia Xi et autres

Preeclampsia (PE) is a severe pregnancy-specific disorder that poses significant risks to maternal and perinatal health. The pathophysiological mechanisms underlying PE are complex and not yet fully elucidated. This study focuses on the role of ferroptosis in PE and identifies a significant …

cn (code pays fourni par la source)

Postpartum depression risk prediction using explainable machine learning algorithms

Xudong Huang, Lifeng Zhang, Chenyang Zhang, Jing Li et autres

Objective: Postpartum depression (PPD) is a common and serious mental health complication after childbirth, with potential negative consequences for both the mother and her infant. This study aimed to develop an explainable machine learning model to predict the risk of PPD and …

cn (code pays fourni par la source)

Postpartum depression in Northeastern China: a cross-sectional study 6 weeks after giving birth

Xudong Huang, Lifeng Zhang, ChenYang Zhang, Jing Li et autres

Introduction: Postpartum depression (PPD) is a prevalent mental health issue that poses significant challenges to maternal wellbeing and infant development. We aimed to determine the prevalence of PPD and to investigate its associated determinants and predictors in in Shenyang, China. Methods: < …

cn (code pays fourni par la source)

Clinical application value of targeted amplicon sequencing technology in fetuses with uniparental disomy-related imprinting disorders: a multicenter study

Ning Liu, Sheng‐Wen Huang, Bin Zhang, Yi Yuan Zhou et autres

cn (code pays fourni par la source)

EfficientMFRF-BiFPN: A CNN-Transformer Hybrid With Multi-Feature Representation Fusion for Pneumonia Detection

Kerang Cao, K. Zhang, Lili Li, Hoe-Kyung Jung

Pneumonia remains a significant global health threat, especially in vulnerable populations, and early, accurate diagnosis is critical for effective intervention. While deep learning has significantly advanced medical image analysis, most existing architectures remain limited in their ability to jointly model local lesion …

cn, kr (code pays fourni par la source)

A case of posterior urethral valve diagnosed by ultrasound in antenatal and pathology: A case report

Jinmei Gao, Junling Kang, Wei Zhang

RATIONALE: Posterior urethral valve is a rare disease, prenatal diagnosis and prognosis evaluation are particularly important. PATIENT CONCERNS: A 25-year-old pregnant woman was found enhanced parenchymal echo in both kidneys, subcapsule urinary cyst formation in both kidneys, bladder enlargement of the fetus …

cn (code pays fourni par la source)

Epigenetics-targeted drugs: current paradigms and future challenges

Wanlin Dai, Xinbo Qiao, Yuanyuan Fang, Rongxia Guo et autres

Epigenetics governs a chromatin state regulatory system through five key mechanisms: DNA modification, histone modification, RNA modification, chromatin remodeling, and non-coding RNA regulation. These mechanisms and their associated enzymes convey genetic information independently of DNA base sequences, playing essential roles in organismal …

cn, us (code pays fourni par la source)

The association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and non-alcoholic fatty liver disease in US adults: a cross-sectional study

Xudong Huang, Jing Li, Lifeng Zhang, ChenYang Zhang et autres

The ratio of non-high-density lipoprotein cholesterol (non-HDL-C) to HDL-C (NHHR) is a novel lipid parameter used to assess the risk of cardiovascular disease. Previous studies have demonstrated an association between the NHHR and risk of non-alcoholic fatty liver disease (NAFLD). Owing to …

cn (code pays fourni par la source)

Hypoxia-induced miR-181a-5p up-regulation reduces epirubicin sensitivity in breast cancer cells through inhibiting EPDR1/TRPC1 to activate PI3K/AKT signaling pathway

Yunwei Zhang, Yunping Guan, Xinyu Zheng, Chenyang Li

Breast carcinoma (BC) ranks as a predominant malignancy and constitutes the second principal cause of mortality among women globally. Epirubicin stands as the drug of choice for BC therapeutics. Nevertheless, the emergence of chemoresistance has significantly curtailed its therapeutic efficacy. The resistance …

cn (code pays fourni par la source)

Effects of miR-204-5p and Target Gene EphB2 on Cognitive Impairment Induced by Aluminum Exposure in Rats

Wei Liu, Jie Gao, Niping Hao, Jing Li et autres

cn (code pays fourni par la source)

The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction

Jie Gao, Wei Liu, Jing Pei, Jing Li et autres

cn (code pays fourni par la source)