Advanced Technologies and Laboratories International (United States)

Occupational exposures to illicit drugs in forensic science divisions

Jennie Cox, J.R. Bartels, Mamadou Niang, Jessica Li et autres

Forensic scientists from local, county, state, and federal law enforcement agencies analyze evidence daily in which unknown substances suspected of containing illicit drugs are handled, weighed, and chemically processed. To address concerns about potential occupational exposures to opioids like fentanyl and other …

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Double dissociation of the effects of volitional control on perceptual selection and maintenance in multistable visual perception

David W. Bressler, Sean Noah, Andrew C. Lu, Michael A. Silver

Stimuli that give rise to multistable percepts are powerful tools for understanding the psychological and neural processes and mechanisms that create conscious perception. Research on multistable perception has resulted in substantial insights regarding the stimulus and configural factors that influence perceptual interpretations …

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Evaluating occupational exposures to the graphene family of nanomaterials: Implications for worker safety and health

Matthew M. Dahm, Seth McCormick, Mamadou Niang, Brian Christensen et autres

Graphene, a two-dimensional carbon-based nanomaterial, has garnered significant attention due to its exceptional physical and chemical properties, leading to its widespread application in various industries. However, the increasing utilization of this class of materials, also referred to as the graphene family of …

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Preventing and Managing Chronic Disease in the Work Environment: Using the Total Worker Health Approach

John Howard, Paul A. Schulte

Occupational health hazards can exacerbate pre-existing chronic diseases and can also lead to the onset of new job-related chronic diseases. A comprehensive strategy to eliminate the root causes of chronic diseases in America should include not only those causes arising from lifestyle …

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COVID-19 Workplace Testing Study

Dalia E. Nessim, Matthew S. Thiese, Cynthia Ball, Jeffrey Levin et autres

BACKGROUND: US businesses were considerably impacted by the COVID-19 pandemic. Return to work after exposure or illness was challenging. OBJECTIVE: This study aimed to assess employers' experiences and perspectives during the pandemic with SARS-CoV-2 testing in their workforce. METHODS: An anonymous survey …

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Abstract 5225: Engineered signaling reporter immune cell lines for monitoring immune activation and multidirectional interactions among cancer cells, immune cells, and tumor microenvironmental cells

Hyeyoun Chang, Alicia C. Walker, John G. Foulke, Luping Chen et autres

While immunotherapies targeting T cells have achieved remarkable success, a significant subset of patients remain unresponsive or experience relapse, often attributed to the immunosuppressive nature of the tumor microenvironment. Emerging evidence suggests that other immune cell types, such as B cells and …

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Abstract 3187: Assessing large-scale CAR-T cell cytotoxicity ex vivo using 2-D and 3-D multimodal imaging techniques for industrial standards

Catherine E. McManus, John G. Foulke, Meghan C Sikes, Luping Chen et autres

Abstract CAR-T cell therapy is a revolutionary and highly effective treatment for hematologic malignancies, with rapid advancements particularly in applications to solid tumors. The development and refinement of this innovative therapy rely on efficient ex vivo assays to evaluate CAR-T cell cytotoxicity. …

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Psychosocial risks and ethical implications of technology: considerations for decent work

Paul A. Schulte, Jessica M. K. Streit

Decent work, a United Nations Sustainable Development Goal, is built on the ethical treatment of workers and ensures respect of their security, freedom, equity, and dignity. In the future, a wide range of technological forces may pose significant impediments to the availability …

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В поисках справедливого суда и правосудия : Экспертное сообщество юристов-криминалистов на рубеже XIX–XX вв.

Anastasiya Tumanova

L’auteure présente un fragment d’une réforme à grande échelle du système judiciaire russe réalisée au tournant du xxe siècle avec la participation de la communauté professionnelle de criminologues qui se formait à cette époque. Elle considère de son devoir de montrer que …

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Application of the Tier 3 NIOSH occupational exposure banding process for the graphene family of nanomaterials: A case study

Mamadou Niang, Nicole Barcellos, Lilia Chen, Seth McCormick et autres

Graphene is a class of two-dimensional (2D) nanomaterials composed of single or multiple layers of carbon atoms. To date, there are limited clinical data and no epidemiological research available to assess graphene toxicity in humans. Despite the growing amount of animal toxicity …

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Advancements in human cell line cryopreservation for assay-ready efficiency

Lukas Underwood, Jacqueline Mikhaylov, Nilay Chakraborty

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The role of cryobiology in implementing advanced cell models

Ruth R. Cheng

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