Pearl River Community College

Layered Reasoning and the Consensus Verification Framework: A Reflective Engineering Case Study of AI-Assisted Decision Verification

Gabor Zoltan Nyarfadi

Engineering decisions increasingly rely on collaboration between human experts and multiple AI systems. While existing approaches often evaluate individual model performance, comparatively little attention has been given to how independent reasoning processes can be combined to improve confidence in engineering decisions. This …

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Problematic Pornography Use in the Middle East: What We Know and What We Don’t - A Scoping Review

Robin Engelhardt, Nicholas C. Borgogna, Canaan Ray, Mahdieh Jafari et autres

Abstract Purpose of Review Problematic pornography use (PPU) has become an increasingly recognized mental health concern worldwide. Nonetheless, empirical research remains heavily concentrated in Western or East Asian contexts, leaving the Middle East – where cultural and sexual norms may shape PPU …

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Abstract LB467: Dose optimization and exposure-response (ER) analysis for PF-08634404, an investigational anti-PD-1 and anti-VEGF bispecific antibody

Erik Hahn, Alan Liu, Donald Irby, Nathan Braniff et autres

Abstract Introduction: Despite advances in therapy for non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), patients ultimately progress and some do not respond, underscoring the need for innovative agents. Given the role of PD-1 and VEGF pathways in tumor growth via …

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Vaccines against antimicrobial resistance

Annaliesa S. Anderson

Antimicrobial resistance (AMR) is a global clinical and economic threat due to the impact that it has on how potentially deadly infections can be treated. Without intervention, it is estimated that AMR will be responsible for 10 million deaths a year by …

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A ‘useless marsh … breeding fever and insect pests’: assessing malaria risk on roads through Cilicia Pedias (modern Türkiye) and its historical impact in antiquity and the Middle Ages

Daniel Browning, John Mark Nicovich

Abstract Historical accounts suggest that malaria was endemic in ancient southern Anatolia, possibly as early as 800 BCE, but overwhelmingly from classical antiquity onwards. However, measuring the level and extent of malaria risk for premodern periods remains difficult, given the lack of …

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P-1467. Clinical Development of MenABCWY (PenbrayaTM), a Broadly Protective Pentavalent Meningococcal Vaccine

Lefteris Zolotas, Ashlesh K. Murthy, Roger Maansson, Ryan Newton et autres

Abstract Background The first-in-class pentavalent meningococcal serogroup A/B/C/W/Y vaccine (MenABCWY; PenbrayaTM) received US licensure in 2023 as a 2-dose, 0,6-month (m) series for individuals 10‒25 years (y) of age. Here we review data supporting MenABCWY licensure and utility. Methods Three phase 1/2b/3 …

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Analysis and Reassessment of Double-Crescent Symbols Purported to Represent Jewish Menorahs in Olbian Rough Cilicia

Daniel Browning, David MALTSBERGER

Doğu Dağlık Kilikia’daki Olba bölgesi, Hellenistik Dönem’den başlayarak mimari yüzeylere kabartma olarak oyulmuş sembollerin belirgin özelliğini sergileyen kalıntılarla doludur. Çeşitli tanrılarla ilişkilendirilen bu sözde “Olba sembolleri”, Hristiyan haçları Bizans Dönemi’nde bir ara pagan sembollerinin yerini alana kadar sonraki dönemlerde devam eden yerel …

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Structure-Based Design of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine

Natalie C. Silmon de Monerri, Ye Che, Joshua A. Lees, J. Jasti et autres

Abstract Adhesion of E. coli to the urinary tract epithelium is a critical step in establishing urinary tract infections. FimH is an adhesin positioned on the fimbrial tip which binds to mannosylated proteins on the urinary tract epithelium via its lectin domain …

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Close-range photogrammetry for analysis of rock relief details: An investigation of symbols purported to be Jewish Menorahs in Rough Cilicia

Daniel Browning

Close-range photogrammetry of certain rock reliefs in Rough Cilicia was used to investigate published claims that symbols in them represent Jewish menorahs, but with five branches instead of the usual seven. Details of ancient rock reliefs are difficult to assess because of …

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Adapt It! Create Your Own Skyscraper Puzzles

Susan Boyd, Liza Bondurant, A. Johnson

A puzzle task is adapted for students to not only solve but create their own. This task promotes problem solving, perseverance, and students’ spatial thinking.

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Safety and Immunogenicity of a Nipah Virus Vaccine (Hev-Sg-V) in Adults: A Single-Centre, Randomised, Observer-Blind, Placebo-Controlled, Phase 1 Study

Robert W. Frenck, Abdi Naficy, Jodi Feser, Michael A. Egan et autres

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Not Just Non-Consensual Pelvic Exams

Shelby Harriel - Hidlebaugh

Photo by National Cancer Institute on Unsplash ABSTRACT Medical professionals sometimes perform intimate tasks while prepping patients for surgical procedures. These tasks may include urinary catheterization, underwear or gown removal, pubic hair removal, and groin sanitization. The intimate nature of these tasks …

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