Dissecting the TMEM132A-EGFR Dependency to Unlock Translational Therapeutic Opportunities for Pan-Solid Tumor
Yaru Fu, Qiqi Ni, Junhao Wang, Mingyu Wu et autres
Abstract Solid tumors remain refractory to conventional treatments, yet cell surface proteins, by virtue of their extracellular accessibility and critical roles in tumor signaling, represent an attractive class of targets for precision-targeted therapy. Here, we report that transmembrane protein 132A (TMEM132A) is …
cn, hk (code pays fourni par la source)
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bioRxiv (Cold Spring Harbor Laboratory)