Foamy microglia link oxylipins to disease progression in multiple sclerosis
Netherlands Brain Bank, Daan van der Vliet, Xinyu Di, Tatiana M. Shamorkina et autres
Multiple sclerosis (MS) is a chronic neuroinflammatory disease in which demyelinating white matter lesions accumulate and expand, driving irreversible disability. Here we identify a distinct population of foamy GPNMB + microglia/macrophages associated with lesion expansion in secondary progressive MS. Using integrated lipidomic, …
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Utrecht University Repository (Utrecht University)