Transcriptome signatures associated with cognitively unimpaired individuals with pathologically confirmed Alzheimer disease
Donghe Li, Xudong Han, Ting F. A. Ang, Joseph N Palmisano et autres
There is growing interest in cognitive resilience to Alzheimer’s disease (AD), given limited success of therapies targeting hallmark proteins. Gene expression in the prefrontal cortex region obtained from brain donors in three cohorts was compared among pathological controls and pathological confirmed AD …
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