Decoding Treg diversity and dysfunction to advance Treg-based therapies in autoimmune and inflammatory diseases
Austin McKay, J. Agustin Cruz, Ian Taylor, Keith Mitchell et autres
Regulatory T cells (Tregs) orchestrate immune tolerance, tissue homeostasis, and tissue repair, and their dysfunction contributes to autoimmune and inflammatory diseases. Rather than representing a uniform lineage, Tregs comprise specialized cellular states shaped by developmental origin, antigen specificity, tissue localization, and environmental …
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Frontiers in Immunology