Targeting oncogenic NTSR1 with liensinine reprograms Gq-mediated signaling to suppress lung adenocarcinoma
Yongfu Wang, Wei Liu, Pengzhuo Tao, Changmin Liu et autres
BACKGROUND: Lung adenocarcinoma (LUAD) is a leading cause of cancer death. Neurotensin receptor 1 (NTSR1), a G protein-coupled receptor, is overexpressed in LUAD and linked to poor prognosis, but its therapeutic potential is underexplored. METHODS: This study combined multi-database bioinformatics to systematically …
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Chinese Medicine