Diagnostic delay and clinical outcomes of paroxysmal nocturnal hemoglobinuria: a retrospective cohort study using Japanese claims data
Yasutaka Ueda, Tatsuya Kawaguchi, Takayuki Ikezoe, Akihiko Shimono et autres
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, potentially life-threatening hematologic disease, often misdiagnosed because of its non-specific symptoms. PNH is characterized by terminal complement activity and intravascular hemolysis, potentially leading to thrombosis, kidney failure, and premature mortality. Early identification remains challenging, necessitating …
jp, ch (code pays fourni par la source)
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International Journal of Hematology